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Interaction of genomic and non-genomic actions of hormones on the nervous system

Interaction of genomic and non-genomic actions of hormones on the nervous system
激素对神经系统的基因组和非基因组作用的相互作用
批准号:
20240036
负责人:
KAWATA Mitsuhiro
金额:
$17.97万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (A)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010

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中文摘要
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英文摘要
The present project was undertaken to reveal the interaction of genomic and non-genomic actions of steroid hormones in the nervous system. The study demonstrated the genomic actions of steroid hormones through specific nuclear receptors and non-genomic actions through membrane steroid receptors by using molecular imaging technique, immunohistochemistry and transgenic mouse. The effects of genomic and non-genomic action on brain sexual differentiation and stress responses during critical period were also investigated behaviorally.
期刊论文(31)
专著(0)
科研奖励(0)
会议论文
アンドロゲン受容体の細胞内動態
雄激素受体的细胞内动力学
DOI: --
发表时间: 2010
期刊:
影响因子: --
作者: [高田悠, 萬代雅希, 木谷友哉, 渡辺尚, 河田光博]
通讯作者: 河田光博
Intranuclear mobility of estrogen receptor a and progesterone receptors in association with nuclear matrix dynamics.
雌激素受体 a 和孕激素受体的核内迁移率与核基质动力学相关。
DOI: --
发表时间: 2008
期刊: Cell Biochem 103
影响因子: --
作者: [Matsuda K, Nishi M, Takaya H, Kaku N, Kawata M]
通讯作者: Kawata M
DOI: 10.1002/glia.20977
发表时间: 2010-06
期刊: Glia
影响因子: 6.2
作者: [Shinsuke Morisaki;M. Nishi;H. Fujiwara;R. Oda;M. Kawata;T. Kubo]
通讯作者: Shinsuke Morisaki;M. Nishi;H. Fujiwara;R. Oda;M. Kawata;T. Kubo
Neuroanatomy in Neuroendocrinology : Neuroanatomy is not just an anatomy, but a mother of physiology or neuroendocrinology. Lecture
神经内分泌学中的神经解剖学:神经解剖学不仅仅是解剖学,而且是生理学或神经内分泌学之母。
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [Hayashi, Y., Karam K., Hayashi M., Matsuura K., Narayanan R., Lakhanpal G., Okamoto K., 河田光博]
通讯作者: 河田光博
29
    Structural analysis of molecular and behavioral neuroendocrinology on the sexual difference and hormonal action in the nervous system
    • 批准号:
      24300128
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $12.06万
    • 财政年份:
      2012
    • 负责人:
      KAWATA Mitsuhiro
    • 依托单位:
    Steroid hormones and their receptor interaction by Raman spectrometer analysis
    • 批准号:
      22659040
    • 项目类别:
      Grant-in-Aid for Challenging Exploratory Research
    • 资助金额:
      $1.98万
    • 财政年份:
      2010
    • 负责人:
      KAWATA Mitsuhiro
    • 依托单位:
    Environmental Effects on the Dynamism of Receptors of Lipophilic Signal Molecules in the Brain and its Functional Significance
    • 批准号:
      16200026
    • 项目类别:
      Grant-in-Aid for Scientific Research (A)
    • 资助金额:
      $31.62万
    • 财政年份:
      2004
    • 负责人:
      KAWATA Mitsuhiro
    • 依托单位:
    DYNAMICS AND REGULATION OF NUCLEAR RECEPTORS OF LIPID SOLUBLE MOLECULE IDENTIFIED BY USING GFPS
    • 批准号:
      13470005
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $10.3万
    • 财政年份:
      2001
    • 负责人:
      KAWATA Mitsuhiro
    • 依托单位:
    海外基金