Development of High-Power Pulsed Microplasma for Analysis of Small Amount Samples

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In recent years, there is growing interest in element analysis for small samples such as bio-cells. In this study, high power pulsed microplasma source and droplet direct injection nebulizer(D-DIN) system were developed. The maximum input power of 55 kW was achieved and about 10, 000 times higher emission intensity compared with DC discharge was obtained. D-DIN was applied to microplasma and absolute detection limit of 3. 2 ag with sodium was achieved. It was less than 1/1, 000, 000 compare with conventional ICP-MS. Finally, single cell analysis of yeast cell was achieved using D-DIN-ICP-MS.