Identification of major host genes involved in the malaria parasite proliferation using mice.
Identification of major host genes involved in the malaria parasite proliferation using mice.
使用小鼠鉴定参与疟疾寄生虫增殖的主要宿主基因。
批准号：
24800031
负责人：
UNNO AKIHIRO
金额：
$1.91万
依托单位：
依托单位国家：
日本
项目类别：
Grant-in-Aid for Research Activity Start-up
财政年份：
2012
资助国家：
日本
项目状态：
已结题
起止时间：
2012-08-31 至 2014-03-31
中文摘要
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英文摘要
The aim of this study was to examine host genes conferring resistance to infection with the malaria parasite in the Pymr1 locus on mouse Chr.9. (1) Using real-time PCR analysis, we detected that several mRNA levels were higher in malaria-susceptible mice than in malaria-resistant mice. (2) To examine the effects of the gene overexpression on resistance to infection with the parasite, we tried to generate TG mouse lines using mouse BAC clone. Susceptibility analyses using these TG mice are still in preparation.
期刊论文(3)
专著(0)
科研奖励(0)
会议论文
DOI：
10.1016/j.parint.2013.10.008
发表时间：
2014-04
期刊：
Parasitology international
影响因子：
1.9
作者：
[Takeshi Hayashi;A. Unno;Minami Baba;T. Ohno;K. Kitoh;Y. Takashima]
通讯作者：
Takeshi Hayashi;A. Unno;Minami Baba;T. Ohno;K. Kitoh;Y. Takashima
海外基金
