Development of the fibrointegrated implant

种植体的成功或失败取决于获得牢固的骨整合。尽管实现了牢固的骨结合，但种植体周围软组织的防御机制并不存在于天然牙之外，这就是种植体周围炎容易诱发并具有脱落危险的原因。从这个角度来看，本项目提出的纤维整合种植体对上皮下结缔组织的牢固附着似乎是重要的，以防止骨吸收。在植入体子宫颈表面进行提前回收，以人工制造锋利的纤维。在植入体表面具有约3 μm的表面形状，并且获得了有效形成植入体作为孔径大于50 μm的锐纤维的组织的信息。对表面质量和纤维附着的影响进行了改性研究。尝试了考虑表面电荷的表面设计。对具有镜面性的纯钛板进行了离子注入处理（Ca+、N+、F+）、阳极氧化、二氧化钛低温热喷涂处理、离子镀处理（TiN、氧化铝）、离子束混合处理（Ag、Sn、Zn、Pt）的耐磨表面处理，获得了基本数据。指出了今后研制可停止漱口和漱口药物应用、可诱导停止细菌粘附或细菌粘附的抗体的人工唾液的必要性，包括临床应用。

The success or failure of the dental implant depends on the acquisition of the firm osseointegration. Eventhough, firm osseointegration was achieved, the defense mechanism of soft tissue around the implant does not exist further than the natural tooth and this is the reason why peri-implantitis is easy to be induced and always has the danger of the falling. From this point of view, the firm attachment of the connective tissue under the epithelium by fibrointegrated implant raised by this project seems to be important in order to prevent the bone resorption. The retrieval was advanced on the surface given to the implant cervix in order to artificially make the sharpy fiber. It had the ruggedness of about 3 μm as a surface shape on the implant surface, and information of being effective in order to form the organization that the implant as an aperture with the hole over 50 μm is sharpy fibers was obtained.On the surface quality with the effect in the fibrous attachment, the modification was studied. Surface design considering the surface charge was tried. It was possible that it conducted ion implantation processing (Ca+, N+, F+), anodization, titania low temperature thermal spraying processing, ion plating processing (TiN, Alumina), abrasion resistant surface treatment of ion beam mixing processing (Ag, Sn, Zn, Pt) to the pure titanium plate of the specularity and obtains basic data.The necessity of the development of the artificial saliva which will stop application of gargling and mouth rinsing medicine, induction of the antibody which stops the bacteria adhesion or bacteria adhesion including clinical application in future is indicated.