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The mechanism of the higher brain function deterioration after cerebral apoplexy using the high field magnetic resonance diffusion tensor imaging.

The mechanism of the higher brain function deterioration after cerebral apoplexy using the high field magnetic resonance diffusion tensor imaging.
利用高场磁共振扩散张量成像研究脑中风后高级脑功能恶化的机制。
批准号:
14370445
负责人:
OGAWA Akira
金额:
$8.26万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2002
资助国家:
日本
项目状态:
已结题
起止时间:
2002 至 2003

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中文摘要
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英文摘要
Increase in the bedridden patient after cerebral apoplexy has become a social problem in the this country though a death rate from the cerebrovascular disorder saw fixed repression with the medical progress. The mechanism of the higher brain function deterioration wasn't definite in comparison with the occurrence mechanism such as the limbs paralysis.As for this research, the elucidation of the higher brain function deterioration mechanism was done after the cerebral apoplexy. Magnetic resonance (MR) diffusion tensor images were adopted as a technique that an image evaluated the higher brain functional disorder. The fractional anisotropy (FA) value was used as the quantitative index of diffusion tensor. Preoperative FA values in the ipsilateral side were significantly lower than those in the contralateral side in the patients with chronic ischemic brain. After surgery, the FA value was significantly increased. Diffusion tensor imaging may indicate isehemic brain damage, not visualized by conventional MR imaging, in patients with chronic ischemic brain.This was connected with as well proving the clinical utility of the high field MR imaging.It was estimated with a brain perfusion image that how many cerebral blood flow declines were the range of the surgical medical treatment again. The amount of cerebral blood flow was greatly concerned with the higher brain function. The mechanism of the higher brain functional deterioration after cerebral apoplexy has been evaluated in this research.
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会议论文
Inoue T: "Preoperaive evaluation of malignancy in gliomas using diffusion tensor imaging"ISMRM. (in press).
Inoue T:“使用扩散张量成像术前评估神经胶质瘤的恶性肿瘤”ISMRM。
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通讯作者:
Kashimura H et al.: "Preoperative evaluation of neural tracts using three-dimensional anisotropy contrast imaging in a patient with brain stem cavernous angioma Case report."Neurosurgery. 52. 1226-1230 (2003)
Kashimura H 等人:“使用三维各向异性对比成像对脑干海绵状血管瘤患者的神经束进行术前评估病例报告。”神经外科。
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通讯作者:
Ogasawara K et al.: "Prediction and Monitoring of Cerebral Hyperfusion After Carotid Endarterectomy by Using Single-Photon Emission computerized Tomography Scanning."J Neurosurg. 99. 504-510 (2003)
Ogasawara K 等人:“通过使用单光子发射计算机断层扫描来预测和监测颈动脉内膜切除术后的脑过度灌注。”神经外科杂志。
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通讯作者:
Inoue T et al.: "Three-dimensional anisotropy contrast imaging of gliomatosis cerebri : two case reports."Surg Neurol. (in press).
Inoue T 等人:“脑胶质瘤病的三维各向异性对比成像:两个病例报告。”Surg Neurol。
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