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Study of 3D Fundus Pattern Reconstruction and Display from Fundus Images

眼底图像3D眼底图案重建与显示研究

基本信息

批准号：
12450161
负责人：
DEGUCHI Koichiro
金额：
$ 7.87万
依托单位：
Tohoku University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (B)
财政年份：
2000
资助国家：
日本
起止时间：
2000 至 2002
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-12450161/
关键词：
Image Processing 3D shape Reconstruction Computer Vision Fundus Image Medical Image Stereo system Fundus Camera Image Diagnostics 医用画像処理能動視覚動画像処理立体表示

项目摘要

In this research, we develop a method to reconstruct and display 3D Findus Pattern from a set of multiple Findus Images taken in many directions. The fundus is the inner bottom of an eyeball. It is the only place in our bodies where blood vessels are able to be observed directly, and it is very useful part for a variety of diagnosis on helth conditions. However, it is difficult to locate the 3D positions of the fundus parts position and measure their dimensions, because the fundus observation is made through eye lens. Due to this, the diagnosis is tend to be emphasized on the subjectivity of the viewers.Some methods have been proposed where, after camera calibrations, 3D fundus display was obtained from a pair of stereo images. But it provided only a narrow area of 3D fundus because of the limited view angle of the fundus camera.In this research, we proposed the method of 3D Reconstruction of large area and showed the experimental results for some real fundus images.Findus images are skewed due to optical systems such camera lens and eye lens. The camera optical system can be fully calibrated, while the human eye system is difficult to be calibrated. In the proposed system, the optical system of the eye is modeled with a single lens, and the shape of the fundus is assumed to be sphere. It is proven that the real images of fundus through a single lens form quadratic surfaces. The deformation of fundus images reflects the parameters of the quadratic surfaces. So, from the multiple fundus images, the parameters were identified, and through which the skews were estimated. Then the 3D display in large area was achieved.To put our result to practical use, it still needs some doctors' help. But many experimental results promise the usefulness of the developed method. This is also a development of new area in the field of computer vision.

在这项研究中，我们开发了一种方法，可以从多个方向拍摄的一组多个 Findus 图像中重建和显示 3D Findus 图案。眼底是眼球的内底部。它是我们体内唯一可以直接观察血管的地方，对于各种健康状况的诊断非常有用。然而，由于眼底观察是通过目镜进行的，因此很难定位眼底部位的3D位置并测量其尺寸。因此，诊断往往强调观看者的主观性。已经提出了一些方法，其中在相机校准之后，从一对立体图像获得3D眼底显示。但由于眼底相机的视角有限，它只能提供狭窄区域的3D眼底。在本研究中，我们提出了大区域3D重建的方法，并展示了一些真实眼底图像的实验结果。由于相机镜头和目镜等光学系统的影响，眼底图像存在倾斜。相机光学系统可以完全标定，而人眼系统则很难标定。在所提出的系统中，眼睛的光学系统用单个镜片建模，并且眼底的形状假设为球体。证明单透镜眼底实像形成二次曲面。眼底图像的变形反映了二次曲面的参数。因此，从多个眼底图像中识别参数，并通过这些参数估计倾斜。然后就实现了大面积的3D显示。要将我们的成果应用到实际中，还需要一些医生的帮助。但许多实验结果证明了所开发方法的实用性。这也是计算机视觉领域的一个新领域的发展。