Inductively Coupled Plasma Triple-Quad Mass Spectrometer and Chromatography (LC-ICP-QQQ)

电感耦合等离子体三重四极杆质谱仪和色谱仪 (LC-ICP-MS/MS)

• 批准号: 460739587
• 金额: --
• 依托单位: Universität des Saarlandes
• 依托单位国家: 德国
• 项目类别: Major Research Instrumentation
• 财政年份: 2021
• 资助国家: 德国
• 起止时间: 2020-12-31 至 无数据
• 项目状态: 未结题
• 来源: https://gepris.dfg.de/gepris/projekt/460739587?language=en
• 关键词: Inductively; Coupled; Plasma; Triple; Quad

One focus of elemental analysis at Saarland University is trace analysis by means of mass spectrometry with inductively coupled plasma (ICP-MS) and elemental speciation by coupling of ICP-MS, in particular with capillary electrophoresis (CE) and liquid chromatography (LC). The requested inductive coupled triple-quadrupole mass spectrometer with coupled liquid chromatography system (LC-ICP-QQQ) is used for the highly sensitive trace analysis of elements and element species in aqueous solutions, which pose a great challenge for analysis, especially in complex environmental samples. The application is a replacement for the outdated ICP MS at the site. The instrument will be a major analytical tool in various research projects in the fields of repository research (trace analysis to investigate the mobility of repository-relevant elements and their speciation with naturally occurring organic matter), water monitoring (quantification, speciation and origin of pollutants in small watercourses), medicine (trace analysis to detect the distribution and accumulation of nanoparticles in various tissues), functional materials (multi-element screening and leaching behaviour of metal-coated antibacterial) and materials science (determination and verification of the chemical composition, degree of functionalisation and decomposition behaviour of nanoscale materials developed in-house). The proposed LC-ICP-QQQ can be used due to its high performance (especially for element trace analysis and element speciation through LC-coupling) and extended measurement range (applications in the field of NanoBioMed) for various current and new research projects at Saarland University.

萨尔大学元素分析的一个重点是用电感耦合等离子体质谱法（ICP-MS）进行痕量分析，用电感耦合等离子体质谱法（ICP-MS）进行元素形态分析，特别是用毛细管电泳（CE）和液相色谱法（LC）。所要求的电感耦合三重四极杆质谱联用液相色谱系统（LC-ICP-QQQ）可用于水溶液中元素和元素种类的高灵敏度痕量分析，这给分析带来了很大的挑战，特别是在复杂的环境样品中。该应用程序是站点上过时的ICP MS的替代品。该仪器将成为储存库研究（痕量分析，以调查储存库相关元素的流动性及其与自然存在的有机物的形态）、水监测（小水道中污染物的量化、形态和起源）、医学（痕量分析，以检测纳米粒子在各种组织中的分布和积累）、功能材料（金属涂层抗菌剂的多元素筛选和浸出行为）和材料科学（内部开发的纳米级材料的化学成分，功能化程度和分解行为的测定和验证）。所提出的LC-ICP-QQQ由于其高性能（特别是通过lc耦合进行元素痕量分析和元素形态分析）和扩展的测量范围（在纳米生物医学领域的应用）可用于萨尔大学的各种当前和新的研究项目。