Development of in-house microangiography using high-intensity quasi-monochromatic x-ray Irradiation from the linear plasma target

使用线性等离子体靶的高强度准单色 X 射线照射开发内部微血管造影术

• 批准号: 13470154
• 负责人: MORI Hidezo
• 金额: $ 9.28万
• 依托单位: National Cardiovascular Center Research Institute
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2001
• 资助国家: 日本
• 起止时间: 2001 至 2003
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-13470154/
• 关键词: Quasi-monocromatic X-ray; Plasma x-ray; Microangiography; Regeneration gtherapy; Myocardial ischemia; Myocardial infarction; Microvessels; Diabetic vasculopathy

The plasma X-ray generator employs a high-voltage power supply, a low impedance coaxial transmission line, a high-voltage power supply, a low impedance coaxial transmission line, a high-voltage condenser with a capacity of 400nF, a turbo-molecular pump, thyrister pulse generator as a trigger device, and a flash x-ray tube. The high-voltage main condenser is charged up to 80 kV by the power supply, and the electric charges in the condenser are discharged to the tube after triggering the cathode electrode. The flush x-ray are then produced. As the electron flows from the cathode electrode are roughly converged to the cerium target by the electric field in the peak tube voltage was almost equal to the initial charging voltage was increased, the linear plasma x-ray source formed and the characteristic x-ray intensities of K-series line increased. The quasi-monochromatic radiography was performed by a new film-less computed radiography system.

等离子体X射线发生器采用高压电源、低阻抗同轴传输线、高压电源、低阻抗同轴传输线、容量为400nF的高压电容器、涡轮分子泵、作为触发装置的晶闸管脉冲发生器和闪光X射线管。高压主电容器由电源充电至80 kV，电容器中的电荷触发阴极电极后释放到管中。然后产生冲洗X射线。当峰值管电压几乎等于初始充电电压时，随着电场的增加，阴极的电子流被大致会聚到铈靶上，形成线性等离子体X射线源，K系列线的特征X射线强度增加。采用新型无胶片计算机X线摄影系统进行准单色摄影。

项目成果

E.Kuwabara, et al.: "Inhomogeneous vasodilatory responses of rat tail arteries to heat stress : Evaluation by synchrotron radiation microangiography"Jpn J Physiol. 52. 403-408 (2002)

E.Kuwabara等人：“大鼠尾动脉对热应激的不均匀血管舒张反应：通过同步辐射显微血管造影进行评估”Jpn J Physiol。

H.Obara, et al.: "Applications of stroboscopic x-ray generators to high-speed radiographies including biomedical applications"SPIE. 4948. 269-274 (2003)

H.Obara 等人：“频闪 X 射线发生器在高速射线照相中的应用，包括生物医学应用”SPIE。

M.Komatsu, et al.: "Low-photon-energy plasma flash x-ray generator (LPFXG-2002)"SPIE. 4948. 574-579 (2003)

M.Komatsu 等人：“低光子能量等离子体闪光 X 射线发生器 (LPFXG-2002)”SPIE。

N.Tokunaga, et al.: "In vivo monitoring of norepinephrine and its metabolites in skeletal muscle"Neurochemistry International. 43. 573-580 (2003)

N.Tokunaga 等人：“骨骼肌中去甲肾上腺素及其代谢物的体内监测”神经化学国际。

E.Sato, et al.: "Quasi-monochromatic parallel flash radiography achieved with a plane-focus x-ray tube"SPIE. 4948. 646-651 (2003)

E.Sato 等人：“使用平面焦点 X 射线管实现的准单色平行闪光射线照相”SPIE。