High-speed Ultracentrifuge Facility with Sensitive Scanning Optics for the Analysis of Interacting Biomolecules

具有灵敏扫描光学器件的高速超速离心机，用于分析相互作用的生物分子

• 批准号: LE0560722
• 负责人: A/Prof Geoffrey Howlett
• 金额: $ 34.19万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Infrastructure, Equipment and Facilities
• 财政年份: 2005
• 资助国家: 澳大利亚
• 起止时间: 2005-01-01 至 2006-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LE0560722
• 关键词: speed; Ultracentrifuge; Facility; Sensitive; Scanning

This request is for a high-speed analytical ultracentrifuge equipped with sensitive absorbance, fluorescence, and interference scanning optics. The equipment, the first of its kind in Australia, would establish a world-class facility for analysing the size, shape, and stability of macromolecular complexes and their interactions in solution. This new facility will enable high through-put screening of small molecules with potential as new drugs. This core platform technology will cover the range of needs from basic research through to commercialization of discovery. The equipment will support existing high quality research projects in biotechnology and provide new opportunities for post-graduate training and international collaboration.

这项要求是为了一种高速分析超速离心机，配备灵敏的吸收、荧光和干涉扫描光学元件。该设备是澳大利亚第一台此类设备，将建立一个世界级的设施，用于分析大分子络合物的大小、形状和稳定性以及它们在溶液中的相互作用。这一新设施将使高通量筛选具有潜力的小分子成为新药。这项核心平台技术将涵盖从基础研究到发现商业化的各种需求。这些设备将支持现有的高质量生物技术研究项目，并为研究生培训和国际合作提供新的机会。