Lypophilic Signal Molecules on Brain Function

亲脂信号分子对脑功能的影响

• 批准号: 14608026
• 负责人: HAYASHI Shinji
• 金额: $ 2.11万
• 依托单位: YOKOHAMA CITY UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2002
• 资助国家: 日本
• 起止时间: 2002 至 无数据
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-14608026/
• 关键词: Steroid hormones; Thyroid hormone; Brain; Symposium; New research field; Receptor protein; Extranuclear action

This research project is to propose new research field to be urgently established. To emphasize the importance of "the lypophilic signal molecules on brain function", we organized two symposia and supported three others listed below that are related to this particular research field.1. International Symposium "Present Status of Steroid Receptors in the Brain" held as as satellite symposium of the 25th Japan Neuroscience Meeting. July 10, 2003, Yokohama. Number of speakers: 8(Organized by this Project)2. "Lypophilic mediators and Receptor Studies", one of the Symposia in the 75th Japan Society of Biochemistry. October 15, 2002, Kyoto, Speakers: 15. (Organized by Kato, S and Shimizu T)3. "Neurosteroids Regulate while Endocrine Disruptors Modify the Memory and Learning" Symposium in the 75th Japan Society of Biochemistry, October 15, 2002, Kyoto. Speakers: 7. (Organized by Kawato, S. and Tsutsui, K)4. "Expression of Sex Difference, views from Brain and Behavior, Environment, Human Society and Culture" March 8, 2003, Kyoto, Speakers: 9 (Organized by this Project)5. "Symposium on Environment and Physiology" a satellite symposium of the 80th Japan Physiology Society, March 23, 2003, Fukuoka. Speakers: 12.(Organized by Sakuma Y)

本研究计画提出新的研究领域亟待建立。为了强调“亲脂性信号分子对大脑功能的重要性”，我们组织了两个研讨会，并支持了以下三个与这一特定研究领域相关的研讨会。作为第25届日本神经科学会议的附属研讨会，召开了“脑中类固醇受体的现状”国际研讨会。2003年7月10日，横滨。演讲人数：8人（本项目组织）2.“亲脂介质和受体研究”，第75届日本生物化学学会研讨会之一。2002年10月15日，京都，发言者：15人。（由Kato，S和Shimizu T整理）3.“神经类固醇调节，而内分泌干扰物修改记忆和学习”研讨会，第75届日本生化学会，2002年10月15日，京都。发言者：7人。（作者：Kawato，S.和Tsutsui，K）4. 2003年3月8日，京都，“性别差异的表现，从大脑和行为、环境、人类社会和文化的观点”，演讲者：9人（本课题主办）5. 2003年3月23日，福冈，第80届日本生理学会卫星研讨会“环境与生理学研讨会”。发言者：12人。（由佐久间Y整理）

项目成果

Towart LA, Alves SE, Znamensky V, Hayashi S, McEwen BS, Milner TA: "Subcellualr relationships between cholinergic terminals and estrogen receptor alpha in the dorsal hippocampus"J. Comp. Neurol.. (in press). (2003)

Towart LA、Alves SE、Znamensky V、Hayashi S、McEwen BS、Milner TA：“背侧海马胆碱能末端和雌激素受体 α 之间的亚细胞关系”J。

Towart LA, Alves Sem Znamensky V, Hayashi S, McEwen BS, Milner TA: "Subcellualr relationships between cholinergic terminals and estrogen receptor alpha in the dorsal hippocampus"J. Comp. Neurol. in press. (2003)

Towart LA、Alves Sem Znamensky V、Hayashi S、McEwen BS、Milner TA：“背侧海马胆碱能末端和雌激素受体 α 之间的亚细胞关系”J。

Tanaka T, Shiina T, Hayashi S, Okamura H, Kamomae H, Kaneda Y: "Estrogen receptor alpha expression in the medial preoptic area and the medial basal hypothalamus under different physiological cnditions in cattle"J. Reprod. Dev.. 49.1. 55-60 (2003)

Tanaka T、Shiina T、Hayashi S、Okamura H、Kamomae H、Kaneda Y：“不同生理条件下牛内侧视前区和内侧基底下丘脑的雌激素受体α表达”J。

Ikeda Y, Nagai A, Ikeda M, Hayashi S: "Increased expression of Mullerian-inhibiting substance correlates with inhibition of follicle growth in the developing ovary of rats treated with E2 benzoate"Endocrinology. 143. 304-312 (2002)

Ikeda Y、Nagai A、Ikeda M、Hayashi S：“苗勒氏管抑制物质表达的增加与用 E2 苯甲酸盐治疗的大鼠发育中卵巢中卵泡生长的抑制相关”内分泌学。

Tanaka T, Shiina T, Hayashi S, Okamura H, Kamomae H, Kaneda Y: "Estrogen receptor alpha expression in the medial preoptic area and the medial basal hypothalamus under different physiological conditions in cattle"J. Reprod. Dev. 49(1). 55-60 (2003)

Tanaka T、Shiina T、Hayashi S、Okamura H、Kamomae H、Kaneda Y：“牛不同生理条件下内侧视前区和内侧基底下丘脑的雌激素受体α表达”J。