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Development of Cancer Treatment System by Induction Heating

感应加热癌症治疗系统的开发

基本信息

批准号：
15300179
负责人：
NAGANO Isamu
金额：
$ 9.92万
依托单位：
Kanazawa University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (B)
财政年份：
2003
资助国家：
日本
起止时间：
2003 至 2004
项目状态：
已结题

项目摘要

-Device developmentIn order to extend the maximum range for cancer treatment, we have improved the first prototype device (which could generate the magnetic field of 3 mT at 40 mm from the induction coil). By increasing the output power to 10kW, the resonance current to 300 A, and the coil diameter to 30 cm, we have been able to realize 3 mT at about 90 mm, which was confirmed by the actual measurement of induced magnetic field strength from the improved device.-Highly effective applicator(a)Use of a high magnetic permeability material (ferrite)The range of the treatment has been further extended to 120 mm, by placing a ferrite board under the coil. From an electromagnetic simulation, we have also confirmed that this ferrite board reduces the electromagnetic waves leaking from the applicator.(b)Use of "litz wire" with low "high-frequency resistance"The copper loss of the applicator on a previous device was as high as 5 kW, because of the high "high-frequency resistance" of the coil wir … More es. Making use of the low "high-frequency resistance" of "litz wire," we have reduced the power consumption of the device by approximately 30%.-DM heating mechanismsIn order to clarify the heating mechanism of Dextran Magnetite (DM), we have measured its "hysteresis loss" by filling the DM solution into a toroidal tube. As a result, we have found that the hysteresis loss occupies about 40 percent of the total amount of DM heating.-Simulation of cooling blood flowThe cooling mechanism of the heated regions due to the blood flow has been examined by a one-dimensional heat conduction simulation.-Eddy current reductionIn the tests using large animals such as pigs, it is necessary to reduce the "eddy current heating" on normal cells. By assuming a simple model, we have found theoretically that the eddy current heating can be reduced even when the DM is sufficiently heated, by adjusting the output frequency of the device as approximately 150 kHz.-Other EMC measurement techniques have been developed associated with the induction heating. Less

-设备开发为了扩大癌症治疗的最大范围，我们改进了第一个原型设备(它可以在40 mm处从感应线圈产生3mT的磁场)。通过将输出功率增加到10kW，谐振电流增加到300A，线圈直径增加到30厘米，我们已经能够在大约90 mm处实现3mT，这一点从改进后的设备的感应磁场强度的实际测量中得到了证实。-高效施加器(A)使用高磁导率材料(铁氧体)通过在线圈下面放置铁氧体电路板，治疗范围进一步扩大到120 mm。通过电磁仿真，我们也证实了这种铁氧体电路板减少了从施加器中泄漏的电磁波。(B)使用具有低高频电阻的LITZ线由于线圈线…的高频电阻高，以前装置上施加器的铜耗高达5kW更多的ES。利用“LITZ导线”的低“高频电阻”，我们将装置的功耗降低了约30%。-DM加热机理为了阐明右旋糖酐磁铁矿(DM)的加热机理，我们将DM溶液注入环形管中，测量了其“磁滞损耗”。结果，我们发现滞后损失约占DM加热总量的40%。-冷却血液流动的模拟通过一维热传导模拟研究了由于血液流动而加热区域的冷却机制。-涡流减少在用猪等大型动物进行的试验中，有必要减少对正常细胞的“涡流加热”。通过假设一个简单的模型，我们从理论上发现，即使在DM被充分加热的情况下，通过将设备的输出频率调整为大约150 kHz，也可以减少涡流加热。-已经开发了与感应加热相关的其他EMC测量技术。较少