Effect of exercise using eccentric contraction on skeletal muscles in rats

离心收缩运动对大鼠骨骼肌的影响

• 批准号: 15500361
• 负责人: KUROKI Hiroshi
• 金额: $ 1.98万
• 依托单位: Kyoto University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2003
• 资助国家: 日本
• 起止时间: 2003 至 2004
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-15500361/
• 关键词: rat; skeletal muscle; eccentric contraction; treadmill; therapeutic exercise

In order to examine the effect of eccentric-contraction exercise on skeletal muscle, rats were suspended from their tail for two weeks (group S), followed by they ran on a horizontal treadmill (60 min per day) for five days (group H ; low eccentric-contraction group) or a downhill treadmill (group D ; high eccentric-contraction group) or no running (group C ; control). Cross-section area of the soleus muscle was 1822.5±311.76μm^2 in group H,1731.3±164.06μm^2 in group D,2120.4±554.34μm^2 in group C and 1619.6±297.91μm^2 in group S, respectively. Number of the muscle fiber for cross-section area of 0.24 m^2 was 83.5±8.23 in group H,73.8±9.91 in group D,73.0±17.05 in group C and 84.3±10.50 in group S, respectively. No significant difference was observed in the cross-section area and number of the muscle fiber in each group. Number of peripheral nucleus in the muscle was 1.8±0.26 in group H,1.8±0.30 in group D,2.5±0.28 in group C and 1.7±0.29 in group S, respectively. The number significantly increased in the group C (p<0.05). These results suggested that recovery of the muscle might be delayed in both of low and high eccentric-contraction exercise groups.

为了研究离心收缩运动对骨骼肌的影响，将大鼠尾部悬吊两周（S组），然后在水平跑步机上（每天60分钟）跑步5天（H组，低离心收缩组）或下坡跑步机上（D组，高离心收缩组）或不跑步（C组，对照组）。H组比目鱼肌横截面积为1822.5±311.76μm^2， D组为1731.3±164.06μm^2， C组为2120.4±554.34μm^2， S组为1619.6±297.91μm^2。横截面积为0.24 m^2时，H组肌纤维数为83.5±8.23条，D组为73.8±9.91条，C组为73.0±17.05条，S组为84.3±10.50条。各组肌肉纤维的横截面积和数量无显著差异。H组、D组、C组、S组分别为1.8±0.26个、1.8±0.30个、2.5±0.28个、1.7±0.29个。C组的数量显著增加（p<0.05）。这些结果表明，在低和高离心收缩运动组中，肌肉的恢复可能被延迟。

项目成果

Effect of exercise using eccentric contraction on skeletal muscles in rats

离心收缩运动对大鼠骨骼肌的影响

• 期刊: Journal of the Japanese Physical Therapy Association (in submission)
• 作者: Hiroshi Kuroki;et al.
• 通讯作者: et al.

遠心性収縮による運動療法がラット骨格筋に及ぼす影響

传出收缩运动疗法对大鼠骨骼肌的影响

• 期刊: 理学療法学 (投稿中)
• 作者: 黒木裕士;ほか
• 通讯作者: ほか