Interrogating the extremes of skeletal muscle plasticity in vertebrates

该项目旨在研究肌肉如何适应生命不同阶段的生长和耐力刺激，以应对世界人口老龄化所面临的挑战。利用斑马鱼和小鼠的创新基因技术和分子生理学，该项目将回答肌肉生物学中重要的、未解决的问题。该项目将产生制定干预措施所需的知识，以改善澳大利亚老年人的生活质量，并解决劳动力老龄化的现实问题。其好处包括提高工作场所的安全性和生产力，提高畜牧业和水产养殖业的养殖效率，以及培训生物科学领域的新兴领导者。

This project aims to interrogate how muscles adapt to growth and endurance stimuli at different stages of life, relevant to addressing challenges facing the world’s ageing population. Using innovative gene technologies and molecular physiology in zebrafish and mice, this project will answer important, unresolved questions in muscle biology. The project will generate knowledge needed to develop interventions to improve quality of life for older Australians and address the physical realities of an ageing workforce. Benefits extend to enhancing workplace safety and productivity, improving farming efficiencies for livestock and aquaculture industries, and training emerging leaders in the biological sciences.