Interrogating the extremes of skeletal muscle plasticity in vertebrates
Interrogating the extremes of skeletal muscle plasticity in vertebrates
批准号:
DP240102721
负责人:
Prof Gordon Lynch
金额:
$35.6万
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2024
资助国家:
澳大利亚
项目状态:
未结题
起止时间:
2024-01-01 至 2026-12-31
中文摘要
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英文摘要
This project aims to interrogate how muscles adapt to growth and endurance stimuli at different stages of life, relevant to addressing challenges facing the world’s ageing population. Using innovative gene technologies and molecular physiology in zebrafish and mice, this project will answer important, unresolved questions in muscle biology. The project will generate knowledge needed to develop interventions to improve quality of life for older Australians and address the physical realities of an ageing workforce. Benefits extend to enhancing workplace safety and productivity, improving farming efficiencies for livestock and aquaculture industries, and training emerging leaders in the biological sciences.
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Age-related mechanisms of amino acid signalling in skeletal muscle
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批准号:DP190101937
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项目类别:Discovery Projects
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资助金额:$35.04万
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财政年份:2019
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负责人:Prof Gordon Lynch
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依托单位:
Therapeutic potential of skeletal muscle plasticity and slow muscle programming for muscular dystrophy
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批准号:nhmrc : GNT1124474
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项目类别:Project Grants
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资助金额:$78.05万
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财政年份:2017
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负责人:Prof Gordon Lynch
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依托单位:
Therapeutic potential of skeletal muscle plasticity and slow muscle programming for muscular dystrophy
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批准号:nhmrc : 1124474
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项目类别:Project Grants
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资助金额:$53.33万
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财政年份:2017
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负责人:Prof Gordon Lynch
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依托单位:
Understanding the cellular cues that direct muscle stem cell specification
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批准号:DP150100206
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项目类别:Discovery Projects
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资助金额:$51.53万
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财政年份:2015
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负责人:Prof Gordon Lynch
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依托单位:
Therapeutic potential of modulating heat shock protein expression for muscle wasting disorder
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批准号:nhmrc : 1065456
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项目类别:Project Grants
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资助金额:$78.16万
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财政年份:2014
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负责人:Prof Gordon Lynch
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依托单位:
Heat shock protein therapy for muscle wasting
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批准号:nhmrc : GNT1065456
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项目类别:Project Grants
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资助金额:$111.37万
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财政年份:2014
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负责人:Prof Gordon Lynch
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依托单位:
Role of suppressor of cytokine signalling proteins (SOCS3) in defective muscle repair and ageing
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批准号:DP120101494
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项目类别:Discovery Projects
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资助金额:$21.48万
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财政年份:2012
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负责人:Prof Gordon Lynch
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依托单位:
Modulating heat shock protein expression in skeletal muscle to improve the pathophysiology of muscular dystrophy
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批准号:nhmrc : 1009114
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项目类别:NHMRC Project Grants
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资助金额:$33.5万
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财政年份:2011
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负责人:Prof Gordon Lynch
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依托单位:
Regulating calcium handling in skeletal muscle - implications for muscle contraction, injury and repair, ageing and development
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批准号:DP0772781
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项目类别:Discovery Projects
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资助金额:$20.16万
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财政年份:2008
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负责人:Prof Gordon Lynch
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依托单位:
Modulating the molecular and cellular physiology of ageing skeletal muscle
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批准号:DP0665071
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项目类别:Discovery Projects
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资助金额:$17.94万
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财政年份:2006
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负责人:Prof Gordon Lynch
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依托单位:
Targeting calcineurin for improving muscle regeneration in skeletal muscle disease
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批准号:nhmrc : 350439
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项目类别:NHMRC Project Grants
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资助金额:$20.2万
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财政年份:2005
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负责人:Prof Gordon Lynch
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依托单位:
THE ROLE OF INTRACELLULAR CALCIUM IN THE MECHANISMS OF INJURY, REGENERATION AND PLASTICITY OF SKELETAL MUSCLE
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批准号:nhmrc : 990801
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项目类别:NHMRC Project Grants
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资助金额:$14.43万
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财政年份:1999
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负责人:Prof Gordon Lynch
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依托单位:
海外基金