Quantitative observation of chemical reactions in solution by use of mass spectrometry.
使用质谱法定量观察溶液中的化学反应。
基本信息
- 批准号:15550065
- 负责人:
- 金额:$ 2.3万
- 依托单位:
- 依托单位国家:日本
- 项目类别:Grant-in-Aid for Scientific Research (C)
- 财政年份:2003
- 资助国家:日本
- 起止时间:2003 至 2004
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
To observe directly some equilibrium reactions in solution such as ion association of di(trialkylammmonium)polymethylene salts in non-aqueous solution (case 1), dissociation of pH indicators (case 2), preparation and reduction of molybdophosphoric acid (case 3), the potentiality of electrospray ionization-mass spectrometry (ESI-MS) had been studied.At first, it became clear that the heat at desolvation plate in ESI module had driven the ion-association. And so, ESI-MS measurements were done without heating at desolvation plate for case 1 and case2. Next, to obtain the quantitative information for case1 and case2, the use of internal standards had been checked up. More adequate standard with comparable structure should be selected to obtaine more significant results, as ionization efficiency was influenced a great deal by the difference of salvation for each tonic species.Mass spoectra for 12-molybdophosphoric acid reduced in the presence of antimony showed that there were two or more species in solution, additionally liquid chromatography (LC) of their samples supported the presence of plural chemical species. In future, the composition and reducing equivalent of each species separated by LC will be become clear by the measurements of ESI-MS and flow-coulometry with column-electrode.
为了直接观察溶液中的某些平衡反应,如双离子缔合反应,本文研究了多亚甲基三烷基铵盐在非水溶液中的分离(例1)、pH指示剂的解离(例2)、正磷酸的制备和还原(例3)、电喷雾电离质谱(ESI-MS)的潜力。很明显,ESI模块中去溶剂化板处的热量驱动了离子缔合。因此,对于情况1和情况2,ESI-MS测量在不加热去溶剂化板的情况下进行。接下来,为了获得病例1和病例2的定量信息,检查了内标物的使用。为了获得更有意义的结果,应选择结构相当的标准品,因为不同的离子化物种的拯救程度对电离效率有很大的影响.在锑存在下还原的12-溴代磷酸的质谱表明,溶液中存在两种或两种以上的物种,此外,其样品的液相色谱(LC)支持存在多个化学物种。今后,通过电喷雾质谱和柱电极流动库仑法的测定,可以更清楚地了解液相色谱分离的各组分的组成和还原当量。
项目成果
期刊论文数量(6)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Preparation and Stereoselectivity of [Cr(L-Amino Acidato)_2 (L-Amino Acidato-N(H_2O)].
[Cr(L-Amino Acidato)_2 (L-Amino Acidato-N(H_2O)]的制备及其立体选择性。
- DOI:
- 发表时间:2003
- 期刊:
- 影响因子:0
- 作者:Hisaya OKI;Ikumi SAWADA;Sachie YOSHIMURA;Ryuji NAKATA
- 通讯作者:Ryuji NAKATA
沖 久也, 澤田育美, 吉村幸絵, 中田隆二: "Preparation and Stereoselectivity of [Cr(L-Amino Acidato)2(L-Amino Acidato-N)(H2O)]"Synthesis and Reactivity in Inorganic and Metal-Organic Chemistry. Vol.33, No.5. 837-846 (2003)
Hisaya Oki、Ikumi Sawada、Yukie Yoshimura、Ryuji Nakata:“[Cr(L-Amino Acidato)2(L-Amino Acidato-N)(H2O)]的制备和立体选择性”无机和金属有机化学中的合成和反应性。第 33 卷,第 5 期。837-846 (2003)
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
- 作者:
- 通讯作者:
Preparation and Stereoselectivity of [Cr(L-Amino Acidato)_2(L-Amino Acidato-N)(H_2O)].
[Cr(L-氨基酸)_2(L-氨基酸-N)(H_2O)]的制备及其立体选择性。
- DOI:
- 发表时间:2003
- 期刊:
- 影响因子:0
- 作者:Hisaya OKI;Ikumi SAWADA;Sachie YOSHIMURA;Ryuji NAKATA
- 通讯作者:Ryuji NAKATA
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NAKATA Ryuji其他文献
NAKATA Ryuji的其他文献
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{{ truncateString('NAKATA Ryuji', 18)}}的其他基金
Development of science teaching materials for energy and environmental education
能源与环境教育科普教材开发
- 批准号:
26350190 - 财政年份:2014
- 资助金额:
$ 2.3万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Development of statinalry-phase and ionohore based on metal-aminoaciato complex with hydrogen-bonding ability
基于具有氢键能力的金属氨基配合物的稳定相和离子载体的开发
- 批准号:
09640720 - 财政年份:1997
- 资助金额:
$ 2.3万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
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