Effect of an alpha-lb adrenoceptor antagonist on methamphetamine-induced neuronal toxicity
Effect of an alpha-lb adrenoceptor antagonist on methamphetamine-induced neuronal toxicity
批准号:
17590228
负责人:
NAKAKI Toshio
金额:
$2.3万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2005
资助国家:
日本
项目状态:
已结题
起止时间:
2005 至 2006
中文摘要
点击翻译按钮获取中文摘要
英文摘要
A nonselective alpha-1 adrenoceptor antagonist prazosin protected methamphetamine-induced neuronal toxicity, while a selective alpha-lb adrenoceptor antagonist failed to do so. We conclude that the neuro-protective effect of prazosin is some unidentified mechanisms other than the alpha-lb receptor blockade.
期刊论文(1)
专著(0)
科研奖励(0)
会议论文
A correlation of METH neurotoxicity with severe hyperthermia in rat striatum
冰毒神经毒性与大鼠纹状体严重高热的相关性
DOI:
--
发表时间:
2007
期刊:
Journal of Pharmacological Sciences 103
影响因子:
--
作者:
[Onohara, N., Nishida, M., Inoue, R., Kobayashi, H., Sumimoto, H., Sato, Y., Mori, Y., Nagao, T., Kurose, H., Utsumi K]
通讯作者:
Utsumi K
A study on CNS oxidative stress-resistant mouse
-
批准号:21590291
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$3.0万
-
财政年份:2009
-
负责人:NAKAKI Toshio
-
依托单位:
Rotenone-Induced Parkinsonism
-
批准号:14570088
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$1.92万
-
财政年份:2002
-
负责人:NAKAKI Toshio
-
依托单位:
Implications of nitrocathecholamines in Parkinson's disease
-
批准号:12680760
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.3万
-
财政年份:2000
-
负责人:NAKAKI Toshio
-
依托单位:
Research on a novel endogenous catecholamine, 6-nitronorepinephrine
-
批准号:09680771
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.3万
-
财政年份:1997
-
负责人:NAKAKI Toshio
-
依托单位:
Development of antihypertensive drugs: L-arginine and its derivatives as a precursor of endothelium-derived relaxing factor
-
批准号:03557012
-
项目类别:Grant-in-Aid for Developmental Scientific Research (B)
-
资助金额:$7.49万
-
财政年份:1991
-
负责人:NAKAKI Toshio
-
依托单位:
海外基金