Neurophysiological sand pathophysiological studies of the human brain function of sensory processing

人脑感觉处理功能的神经生理学和病理生理学研究

• 批准号: 14570588
• 负责人: HOSHIYAMA Minoru
• 金额: $ 2.05万
• 依托单位: Nagoya University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2002
• 资助国家: 日本
• 起止时间: 2002 至 2003
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-14570588/
• 关键词: electroencephalography; evoked brain potentials; somatosensory; magnetic fields; magnetoencephalography; event-related evoked potentials; temporal discrimination; 体性感覚誘発脳反応; 情報処理能力; recovery function; ヒト; 能磁図

During the term of the research (2002-2003), I investigated the sensory processing in the human brain, using evoked potential and evoked magnetic field techniques. For the somatosensory processing, we found the brain could process high frequency stimulation applied on the peripheral up to 1000Hz, although the subject could not recognized each high frequent stimulation at all. The ability to respond to high frequency stimulation was a basic function for the temporal discrimination, which is one of the somesthetic discrimination of human. I studied the temporal discrimination on various part body and also pathological changes by aging. Similarly to the somatosensory system, I investigated the visual function and its temporal resolution. Giving a very short visual stimulus, the brain response for the subliminal stimulation was investigated. I concluded that the subliminal could affect the brain response to the supraliminal visual stimulation. Both in the somatosensory and visual processes, brain responses to the subliminal stimulation might be important and might affect the cognition and behavior after the stimulation.

在研究期间（2002-2003年），我用诱发电位和诱发磁场技术研究了人脑的感觉加工。对于躯体感觉处理，我们发现大脑可以处理施加在外周上高达1000 Hz的高频刺激，尽管受试者根本无法识别每个高频刺激。时间辨别是人类躯体感觉辨别的一种，对高频刺激的反应能力是时间辨别的基本功能。研究了人体各部位的时间分辨力和衰老引起的病理变化。与躯体感觉系统类似，我研究了视觉功能及其时间分辨率。给予一个很短的视觉刺激，研究了大脑对阈下刺激的反应。我的结论是阈下可以影响大脑对阈上视觉刺激的反应。在躯体感觉和视觉过程中，大脑对阈下刺激的反应可能是重要的，并可能影响刺激后的认知和行为。

项目成果

Hoshiyama M.: "New concept for the recovery function of short-latency somatosensory evoked cortical potentials following median nerve stimulation."Clinical Neurophysiology. 113-4. 535-541 (2003)

Hoshiyama M.：“正中神经刺激后短潜伏期体感诱发皮层电位恢复功能的新概念。”临床神经生理学。

Hoshiyama M.: "Changes in somatosensory evoked responses by repetition of the median nerve stimulation"Clinical Neurophysiology. 114・12. 2551-2557 (2003)

Hoshiyama M.：“正中神经刺激的重复引起的体感诱发反应”临床神经生理学 114・12 2551-2557（2003）。

Hoshiyama M.: "Temporal discrimination threshold on various parts of the body."Muscle and Nerve. (印刷中). (2004)

Hoshiyama M.：“身体各个部位的时间辨别阈值。”肌肉和神经（2004 年出版）。

Hoshiyama M.: "Changes in somatosensory evoked responses by repetition of the median nerve stimulation."Clinical Neurophysiology. 114・12. 2551-2557 (2003)

Hoshiyama M.：“正中神经刺激的重复引起的体感诱发反应的变化。”临床神经生理学 114・12 2551-2557（2003）。

Hoshiyama M. Kakigi R.: "New concept for the recovery function of short-latency somatosensory evoked cortical potentials following median nerve stimulation"Clin Neurophysiol.. 113・4. 535-541 (2002)

Hoshiyama M. Kakigi R.：“正中神经刺激后短潜伏期体感诱发皮层电位恢复功能的新概念”Clin Neurophysiol.. 113・4（2002）