Analyses of Signal Transduction Mechanisms based on Protein Structures

基于蛋白质结构的信号转导机制分析

• 批准号: 06276103
• 负责人: NISHIMURA Yoshifumi
• 金额: $ 288.58万
• 依托单位: Yokohama City University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research on Priority Areas
• 财政年份: 1994
• 资助国家: 日本
• 起止时间: 1994 至 1998
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-06276103/
• 关键词: Structural Biology; X-ray Crystallography; NMR; Signal Transduction; Transcription; DNA-binding Proteins; RNA-binding Proteins; Molecular Biology

To encourage collaborative studies between structural and molecular biologists, newsletters containing the research targets and conditions of each member in this project have been published with thirteen issues during 1994 - 1997. To announce research results of this project for other scientists outside the members, many symposia have been held, for example, "Roles of Protein Structures in Signal Transduction and Transcription" in 1994, "Molecular Recognition of Proteins" in 1995, "The Frontiers of Structural Biology", "Molecular Recognition Based on Protein Tertiary Structures" and "Structural Biology on Molecular Recognition of Proteins" in 1996, "Structural Biology of Signal Transduction and Molecular Recognition of DNA/RNA" and "Structural Biology of Reaction Regulation and Molecular Recognition" in 1997, and "Protein Structures in Signal Recognition' in 1998. In addition, we support the "Annual Symposium on Structural Biology" started from 1995. In 1995, a workshop on "Structure Determination of Proteins by X-ray and NMR Methods" was held for young researchers to enter the field of structural biology. For graduate and under graduate students, a Japanese book entitled "The Frontiers of Structural Biology" has been published under the editors that are the members of this project and nearly twenty members of this project have contributed to this book.

为了鼓励结构生物学家和分子生物学家之间的合作研究，在1994-1997年间出版了载有该项目每个成员的研究目标和条件的通讯，共13期。为了向其他成员以外的科学家公布该项目的研究成果，先后举办了许多专题讨论会，例如1994年的《蛋白质结构在信号转导和转录中的作用》，1995年的《蛋白质的分子识别》，1996年的《结构生物学前沿》，1996年的《基于蛋白质三级结构的分子识别》和《蛋白质分子识别的结构生物学》，1997年的《信号转导和DNA/RNA的分子识别的结构生物学》和《反应调控和分子识别的结构生物学》，以及1998年的《信号识别中的蛋白质结构》。此外，我们支持从1995年开始的“结构生物学年度研讨会”。1995年，为进入结构生物学领域的青年研究人员举办了《用X射线和核磁共振方法测定蛋白质的结构》研讨会。对于研究生和研究生，在该项目的成员编辑的领导下，出版了一本名为《结构生物学的前沿》的日语书籍，该项目的近20名成员为这本书做出了贡献。