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Supervision of the Research of Single-cell Molecular Technology

Supervision of the Research of Single-cell Molecular Technology
单细胞分子技术研究监督
批准号:
11227101
负责人:
MATSUOKA Hideaki
金额:
$16.77万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research on Priority Areas
财政年份:
1999
资助国家:
日本
项目状态:
已结题
起止时间:
1999 至 2002

项目摘要

项目成果

MATSUOKA Hideaki的其他基金

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相关文献

中文摘要
翻译
这项研究于1999年10月1日开始,2003年3月31日结束。在前半期(1999.10-2001.3),督导组鼓励每一位研究人员挑战以单细胞分子技术为重点的新研究课题。在后半期(2001.4-2003.3),优先考虑了几个被视为典型单细胞研究对象的对象。例如,“利用单细胞操作辅助机器人开发单细胞实验系统”(A组)、“使用电化学扫描显微镜进行单细胞生物成像”(B组)和“构建由应激反应基因和荧光蛋白报告基因组成的新型原生质体”(C组)。这些研究对象的预期结果被认为是未来创造具有新功能的细胞、组织和动物的发展研究的重要基础。为了讨论这一前景,2002年11月11日至12日举行了题为“从细胞到组织的创造”的研讨会。综上所述,积累了许多关于单细胞的实验技术和研究成果。他们对生物技术和生物科学的贡献是惊人的。
英文摘要
This study started in October 1, 1999 and ended in March 31, 2003. In the former half period (1999.10-2001.3), the supervisor group encouraged every investigator to challenge new research subjects focused on the single-cell molecular technology. In the latter half period (2001.4-2003.3), priority was given to several subjects that were regarded as typical single-cell research subjects. They were, for example, "The development of a single-cell experiment system using single-cell manipulation supporting robot" (A-group), "Single-cell bio-imaging using an electrochemical scanning microscope" (B-group), and "The construction of novel plasimids composed of stress response genes and a fluorescent protein reporter gene" (C-group). The expected results of these research subjects were thought to be the important basis of future developmental study on the creation of cells, tissues, and animals with novel functions. In order to discuss about such a prospect, a symposium entitled "From cells to the creation of tissues" was held on November 11-12, 2002. In summary, many experimental know-hows and study results on single-cells were accumulated. Their contribution to biotechnology and bioscience was remarkably great.
期刊论文(488)
专著(0)
科研奖励(0)
会议论文
K.Suda, J.-T.Woo, M.Takami, P M Sexton, K.Nagai: "Lipopolysaccharide supports survival and fusion of preosteoclasts independent of TNF-alpha, IL-1 and RANKL"J. Cell Physiol.. 190. 101-108 (2002)
K.Suda、J.-T.Woo、M.Takami、PM Sexton、K.Nagai:“脂多糖支持独立于 TNF-α、IL-1 和 RANKL 的前破骨细胞的存活和融合”J。
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K.Igarashi, J-T Woo, P H Stern: "The effects of a selective cyclooxygenase-2 inhibitor, celecoxib, on bone resorption and osteoclastogenesis in vitro"Biochemical Pharmacology. 63. 523-532 (2002)
K.Igarashi、J-T Woo、P H Stern:“选择性环氧合酶 2 抑制剂塞来昔布对体外骨吸收和破骨细胞生成的影响”生化药理学。
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G.Umetsuki: "Involvement of Rnase G in vivo mRNA metabolism in Escherichia coli"Genes Cells. 6. 403-410 (2001)
G.Umetsuki:“大肠杆菌体内 mRNA 代谢中 RNA 酶 G 的参与”Genes Cells。
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K.Watanabe: "Modification Defect at Anticodon Wobble Nucleotide of Mitochondrial tRNAsLeu(UUR) with Pathogenic Mutations of Mitochondrial Myopathy,Encephalopathy.Lactic Acidosis, and Stroke Like Episodes."J.Biol.Chem. 275. 4251-4257 (2000)
K.Watanabe:“线粒体 tRNALeu (UUR) 反密码子摆动核苷酸的修饰缺陷与线粒体肌病、脑病、乳酸性酸中毒和中风样发作的致病性突变。”J.Biol.Chem。
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228
    Analysis of dynamic control mechanism of undifferentiated state in ES cells
    Bio-Cell Gene Expression Analyzer
    Rapid Bioassay with a Bio-Cell Tracer System (BCT)
    Development of an Analyzing System of the Cellular Responses to Multiple Stresses
    海外基金