Downsizing studies on chemical experiments for minimization of environmental loads

减少环境负荷的化学实验小型化研究

基本信息

批准号：
15069207
负责人：
KORENAGA Takashi
金额：
$ 5.89万
依托单位：
Tokyo Metropolitan University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research on Priority Areas
财政年份：
2003
资助国家：
日本
起止时间：
2003 至 2005
项目状态：
已结题

项目摘要

Academic educational activities for decresing experimental wastes on chemical experiments in university laboratories were proper as the title of this program or the scientific research of priority area project, considering the present situations of the environmental, health and safety waste management issues. It was concluded that the research activities would give their suggestion about the new term to the project, considering "downsizing on chemical experiments" to be the key word of the research activities of the important academic research program.Microcolumns were integrated into the micro HPLC systems to reduce hazardous organic solvents. A microchip device for monitoring of the trace gas in the air was developed. The micro device has been developed and optimized in order to measure for atmospheric nitrogen dioxide (NO_2) with high sensitivity. The detection limit was approximately 1 ppb in wind tunnel. The trace gas measurement microchip was composed of two polymethylmethacrylat … More e plates and polytetrafluoroethylene filter as absorbing area. Microchannel was fabricated by injection molding. Under optimized conditions, the microchip-device was tested measurement of NO_2. Comparison with the date generated by the conventional instrument indicated with agreements. Development of a micro reactor for organic synthesis was also carried out in this program. We developed a device for simultaneous determination of benz[a]pyrene (BaP) and benzo[k]fluoranthene (BkF) in diesel exhaust particles and clean-up microchip for pretreatment. About more than 90% of recovery of BaP and BkF in diesel exhaust particle solutions was attained by the clean-up microchip. Combining the clean-up microchip and detection device, detection time could be shortened less than one tenth compared with the conventional method. PAHs in diesel exhaust particle (DEP) were trapped into silica gel beads, which were packed into the microchip, and extracted into chloroform. Pre-treatment system with a microchip reactor was developed for eluting PAHs from DEP. These chemical experimental results with micro scale tools obtained were the same as ordinary bulk scale methods. Less

考虑到当前环境，健康和安全废物管理问题的情况，考虑到该计划的标题或优先区域项目的科学研究，用于化学实验的实验性废物的学术教育活动是适当的。得出的结论是，研究活动将对项目的新术语提出建议，考虑到“化学实验的缩小尺寸”是重要的学术研究计划的研究活动的关键词。MicroColumns被整合到微型HPLC系统中以减少危险有机解决方案。开发了用于监测空气中痕量气体的微芯片设备。为了测量具有高灵敏度的大气氮二氧化氮（NO_2），已开发和优化了微型设备。在风洞中，检测极限约为1 ppb。痕量气体测量微芯片由两个多甲基甲基丙烯酸酯……更多的e板和聚氟乙烯滤波器作为吸收区域。微通道是通过注入成型制造的。在优化的条件下，测试了Microchip设备的NO_2测量。与协议指示的常规工具生成的日期进行比较。在该程序中还进行了微反应器的有机合成。我们开发了一种用于同时测定苯二苯甲酸苯甲酸酯（BAP）和苯并[K]氟烷（BKF）中的装置，并在柴油排气颗粒中和清理微芯片进行预处理。清理微芯片获得了柴油排气颗粒溶液中BAP和BKF恢复的90％以上。与常规方法相比，将清理微芯片和检测装置结合在一起，可缩短检测时间不到十分之一。将柴油排气颗粒（DEP）中的PAH捕获到硅胶珠中，这些硅珠被包装到微芯片中，并提取成氯仿。开发了带有微芯片反应器的预处理系统，用于洗脱DEP的PAH。这些使用显微镜工具的化学实验结果与普通散装量表方法相同。较少的

项目成果

期刊论文数量（70）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Environment, Safety, and Health

环境、安全和健康

DOI：
发表时间：
2006
期刊：
Sankyo Shuppan, Tokyo
影响因子：
0
作者：
Teerada Ruamchat;Ruri Hidano;Eisuke Yonekura;Rumiko Hayashi;Somkiat Ngamprasertsith;Yoshito Oshima;Korenaga T (Editor)
通讯作者：
Korenaga T (Editor)

Determination of iodide in seawater and edible salt by microcolumn liquid chromatography with poly (ethylene glycol) stationary phase.

聚乙二醇固定相微柱液相色谱法测定海水和食用盐中的碘化物。