Comprehensive genomics towards the frontiers of biology and med

我们已经运作了四个委员会，以安排支持其他三个基因组研究领域，即“系统基因组学”、“比较基因组学”和“应用基因组学”，包括1)大规模基因组和cDNA的DNA测序，2)使用全长cDNA技术进行高质量的转录组分析，3)使用SNPs和微卫星进行人类基因组分型，以及4)高度集成的数据库。支持的成果包括Medaka鱼(自然2007)、文昌鱼(自然2008)、野生小鼠、半角鱼、水熊、无尾鞭毛虫卵形和人类肠道的元基因组的基因组测序，以及对II型糖尿病(NAT)等疾病相关基因的GWA分析。吉内。2008)，嗜睡症(NAT.吉内。2008)和颅内动脉瘤(NAT.吉内。2008年)。这些结果表明，这些核心设施和活动对基因组科学是必不可少的。

We have been operating 4 committees to arrange to support thethree other genome research areas, "Systems Genomics", "Comparative Genomics" and"Applied Genomics", as to 1) large-scale DNA sequencing of genomes and cDNAs, 2) highquality transcriptome analysis using the full-length cDNA technology, 3) human genometyping using SNPs and microsatellites and 4) highly integrated database. The outcome ofthe support contains the genome sequencing of Medaka fish (Nature 2007), Amphioxous(Nature 2008), wild-derived mouse, a hemichordata, water bears, the choanoflagellateMonosiga ovata and metagenome of human intestine, and GWAS analysis of diseaserelated genes such as type II diabetes (Nat. Genet. 2008), Narcolepsy (Nat. Genet. 2008)and intracranial aneurysm (Nat. Genet. 2008). These results shows that such core facilitiesand activities are essential for genome sciences.