Comprehensive genomics towards the frontiers of biology and med

我们已经成立了4个委员会，安排支持其他三个基因组研究领域，“系统基因组学”，“比较基因组学”和“应用基因组学”，包括1)基因组和cDNA的大规模DNA测序，2)使用全长cDNA技术的高质量转录组分析，3)使用snp和微卫星的人类基因组分型和4)高度集成的数据库。支持的结果包括Medaka鱼的基因组测序（Nature 2007），文文鱼（Nature 2008），野生小鼠，半虫，水熊，长鞭毛线虫和人类肠道宏基因组，以及疾病相关基因的GWAS分析，如II型糖尿病（Nat. Genet. 2008），嗜睡（Nat. Genet. 2008）和颅内动脉瘤（Nat. Genet. 2008）。这些结果表明，这些核心设施和活动对基因组科学至关重要。

We have been operating 4 committees to arrange to support thethree other genome research areas, "Systems Genomics", "Comparative Genomics" and"Applied Genomics", as to 1) large-scale DNA sequencing of genomes and cDNAs, 2) highquality transcriptome analysis using the full-length cDNA technology, 3) human genometyping using SNPs and microsatellites and 4) highly integrated database. The outcome ofthe support contains the genome sequencing of Medaka fish (Nature 2007), Amphioxous(Nature 2008), wild-derived mouse, a hemichordata, water bears, the choanoflagellateMonosiga ovata and metagenome of human intestine, and GWAS analysis of diseaserelated genes such as type II diabetes (Nat. Genet. 2008), Narcolepsy (Nat. Genet. 2008)and intracranial aneurysm (Nat. Genet. 2008). These results shows that such core facilitiesand activities are essential for genome sciences.