Functional Genomics
Functional Genomics
批准号:
08283105
负责人:
KOHARA Yuji
金额:
$344.26万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research on Priority Areas (A)
财政年份:
1996
资助国家:
日本
项目状态:
已结题
起止时间:
1996 至 2000
中文摘要
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英文摘要
Y. Kohara carried out the systematic analysis of expression patterns of 7000 genes along the time course of development of the nematode C. elegans, and performed the clustering analysis to identify the cis-elements of various regulatory regions. K. Okubo revealed the structure of human transcriptome through the construction of the database named BodyMap which consisted of the expression patterns with respect to anatomy of some 20,000 human genes. S. Sugano developed the Oligo-capping method aiming at constructing full-length enriched cDNA libraries and applied it to the systematic analysis of the transcription start sites in the human genome. T. Itoh established a comprehensive system to examine two-hybrid interactions in all possible combinations between the yeast S, cerevisiae proteins, and predicted several gene cascades base on the identified interactions. N. Ogasawara and collaborators carried out functional analysis of B. subtilis genome through the disruption and phenotype analysis on 2674 genes as a Japan-Europe joint project. K. Kato developed a highly sensitive method named Adapter-tagged Competitive PCR and applied it to gene expression profiling of mouse postnatal cerebellar development. Other projects were also performed as follows. E. Takahashi performed functional analysis of 162 human genes. T. Aigaki generated 2000 GS (gene-search) strains of D. melanogaster to screen various genes. S. Minani developed a highly effective method to generate deletion mutants in C. elegans. A. Sugimoto improved the soaking RNAi method and performed the phenotype analysis of 2500 C. elegans genes. M. Maeda and her collaborators carried out cDNA project of the slime mold D. discoideum. Y. Murakami carried out expression profiling of the all genes of the chromosome VI of S. cerevisiae.
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Masuda N: "Analysis of chemical modification of RNA from formalin-fixed samples and optimization of molecular biology applications for such samples"Nucleic Acids Res.. 27(22). 4436-43 (1999)
Masuda N:“福尔马林固定样品中 RNA 的化学修饰分析以及此类样品的分子生物学应用的优化”《核酸研究》27(22)。
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Shimizu-Matsumoto A.: "Isolation and chromosomal localization of human cone cGMP phosphodiesteraseg cDNA." Genomics.32. 121-124 (1996)
Shimizu-Matsumoto A.:“人锥体 cGMP 磷酸二酯酶 cDNA 的分离和染色体定位。”
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Watanabe T.K.: "Cloning,expression pattern and mapping to 12p13.2->p13.1 of CLAPS3,a gene encoding a novel clathrin-adaptor small chain." Cytogenet Cell Genet. 73. 214-217 (1996)
Watanabe T.K.:“CLAPS3 的克隆、表达模式和 12p13.2->p13.1 定位,CLAPS3 是编码新型网格蛋白接头小链的基因。”
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Ito T.: "An SH3 domain-mediated interaction between the phagocyte NADPH oxidase factors p40phox and p47phox" FEBS Lett.385. 229-232 (1996)
Ito T.:“吞噬细胞 NADPH 氧化酶因子 p40phox 和 p47phox 之间的 SH3 结构域介导的相互作用”FEBS Lett.385。
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Naitou M.: "Sequencing of 23kb fragment,clone gapB and 4682 of Saccharomyces cerevisiae chromosome VI." Yeast. 12. 77-84 (1996)
Naitou M.:“酿酒酵母 VI 号染色体 23kb 片段、克隆间隙 B 和 4682 的测序。”
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共 196 条
Studies on genomic basis for parthenogenesis in nematodes
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批准号:17H03609
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.9万
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财政年份:2017
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负责人:KOHARA Yuji
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依托单位:
Platform for Advanced Genome Science
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批准号:16H06279
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项目类别:Grant-in-Aid for Scientific Research on Innovative Areas ― Platforms for Advanced Technologies and Research Resources
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资助金额:$4926.94万
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财政年份:2016
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负责人:KOHARA Yuji
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依托单位:
Comparative genome analysis of parthenogenetic nematode
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批准号:25250025
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$29.04万
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财政年份:2013
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负责人:KOHARA Yuji
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依托单位:
Expression-pattern based studies on gene regulation network in the nemetode C.elegans
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批准号:22241047
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$24.71万
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财政年份:2010
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负责人:KOHARA Yuji
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依托单位:
Platform of large scale and high quality genomics and bioinformatics: Towards the advancement of genome sciences in academia
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批准号:221S0002
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项目类别:Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
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资助金额:$0.0万
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财政年份:2010
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负责人:KOHARA Yuji
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依托单位:
Large-scale DNA sequencing for comparative systems biology
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批准号:17020009
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项目类别:Grant-in-Aid for Scientific Research on Priority Areas
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资助金额:$481.02万
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财政年份:2005
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负责人:KOHARA Yuji
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依托单位:
Large-scale DNA sequencing and its application
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批准号:17020008
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项目类别:Grant-in-Aid for Scientific Research on Priority Areas
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资助金额:$568.96万
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财政年份:2005
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负责人:KOHARA Yuji
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依托单位:
Comprehensive genomics towards the frontiers of biology and med
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批准号:16066101
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项目类别:Grant-in-Aid for Scientific Research on Priority Areas
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资助金额:$69.5万
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财政年份:2004
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负责人:KOHARA Yuji
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依托单位:
Systematic analysis of expression and function of developmental genes of model organisms towards computer simulation
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批准号:12202003
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项目类别:Grant-in-Aid for Scientific Research on Priority Areas
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资助金额:$245.38万
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财政年份:2000
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负责人:KOHARA Yuji
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依托单位:
Genome science towards the understanding of life
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批准号:12201001
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项目类别:Grant-in-Aid for Scientific Research on Priority Areas
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资助金额:$2079.17万
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财政年份:2000
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负责人:KOHARA Yuji
-
依托单位:
国内基金
海外基金
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FST基因调控猪乳腺原基上皮细胞功能研究及其因果SNP位点鉴定
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