Contact X-ray Cabinet

接触式X射线柜

• 批准号: 503478951
• 金额: --
• 依托单位: Universität Hamburg
• 依托单位国家: 德国
• 项目类别: Major Research Instrumentation
• 财政年份: 2022
• 资助国家: 德国
• 起止时间: 2021-12-31 至 无数据
• 项目状态: 未结题
• 来源: https://gepris.dfg.de/gepris/projekt/503478951?language=en
• 关键词: Contact; ray; Cabinet

The contact x-ray cabinet is required for numerous routinely used methods in osteological research and is an essential basic equipment for our institute. The device applied for is intended to replace an existing X-ray cabinet that has reached the end of its service life and can therefore neither be serviced nor repaired. Spare parts are also no longer available and the X-ray tube currently in use only has a very limited remaining lifespan, which is why timely replacement is urgently required. A functioning X-ray cabinet is required for almost all current research projects at the institute. The applications are very well established and range from orientation aid for sample cutting, control of certain sample preparation processes such as decalcification, identification of phenotypes in large and small animal models, to the generation of images and data that can be used directly for publications, such as bone density and quantification of the skeletal morphology. Furthermore, there are also cooperation projects with various other institutes and facilities, all of which are dependent on a functioning X-ray cabinet in order to work on musculoskeletal questions or to examine fundamentally different aspects with the device. These involve, for example, ectopic mineralization in neuronal tissue or checking the contrasting of soft tissue. The contact X-ray cabinet applied for here has some decisive improvements over the previously available device: The maximum X-ray tube voltage can reach up to 100 kV, which significantly improves the display of extremely compact samples and, in particular, of metallic implants. Furthermore, the enormously enlarged sensor area of 43 x 43 cm has considerable advantages over the old one with only 12 x 12 cm. Larger samples of human origin (e.g. forensic osteology, knee or hip implants) or from large animal models can be displayed in one piece, which enables more efficient and meaningful examinations. But even with smaller samples, this sensor size provides a decisive advantage, as several samples can be displayed in direct comparison at the same time. The extended capabilities of the requested device also enable the development and establishment of new and innovative analysis methods, such as integrated, automated bone density measurement and body composition determination in small animal models. Thus, the requested contact x-ray cabinet is urgently needed to ensure the successful processing of numerous projects in the areas of basic, translational and clinical research as well as in forensics and to ensure the high scientific research performance of our institute in the future.

接触式X线机是骨科研究中许多常规方法所必需的，也是我所必不可少的基本设备。申报器械预期用于替换现有的X射线柜，该X射线柜已达到其使用寿命，因此无法进行维护或维修。零部件也不再可用，目前使用的X射线管的剩余寿命非常有限，这就是迫切需要及时更换的原因。该研究所目前几乎所有的研究项目都需要一个能正常工作的X射线柜。这些应用已经非常成熟，范围从用于样品切割的定向辅助，某些样品制备过程的控制，如脱钙，大型和小型动物模型中表型的识别，到可直接用于出版物的图像和数据的生成，如骨密度和骨骼形态的量化。此外，还与其他各种机构和设施开展了合作项目，所有这些机构和设施都依赖于一个正常运作的X射线柜，以便解决肌肉骨骼问题或使用该设备检查根本不同的方面。这些包括，例如，神经元组织中的异位矿化或检查软组织的对比度。这里应用的接触式X射线柜比之前可用的设备有一些决定性的改进：最大X射线管电压可达100 kV，这显着改善了极其紧凑的样本的显示，特别是金属植入物的显示。此外，43 x 43 cm的大幅扩大的传感器面积比仅为12 x 12 cm的旧传感器具有相当大的优势。更大的人体样本（例如法医骨骼学、膝关节或髋关节植入物）或来自大型动物模型的样本可以以一件式展示，从而实现更有效和更有意义的检查。但即使是较小的样品，这种传感器尺寸也具有决定性的优势，因为可以同时显示多个样品进行直接比较。所要求的设备的扩展功能还可以开发和建立新的创新分析方法，例如在小动物模型中进行集成的自动骨密度测量和身体成分测定。因此，迫切需要所要求的接触式X射线柜，以确保成功处理基础、转化和临床研究以及法医领域的众多项目，并确保我们研究所未来的高科研绩效。