Investigation of the medical/biological roles of the parafibromin functions regulated by SHP2 oncoprotein
Investigation of the medical/biological roles of the parafibromin functions regulated by SHP2 oncoprotein
批准号:
15K18399
负责人:
TAKAHASHI Atsushi
金额:
$2.75万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2015
资助国家:
日本
项目状态:
已结题
起止时间:
2015-04-01 至 2017-03-31
中文摘要
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英文摘要
期刊论文(7)
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LEOPARD症候群特異的変異型SHP2のin vitro脱リン酸化試験による酵素活性解析
LEOPARD综合征特异性突变体SHP2体外去磷酸化酶活性分析
DOI:
--
发表时间:
2016
期刊:
影响因子:
--
作者:
[野田沙織, 高橋昌史, 林剛瑠, 田沼靖一, 畠山昌則]
通讯作者:
畠山昌則
実験医学 11月号 発生・器官形成、がん悪性化に関わるHippoシグナル
实验医学十一月号:河马信号参与发育、器官形成和癌症恶性肿瘤
DOI:
--
发表时间:
2015
期刊:
影响因子:
--
作者:
[高橋昌史, 畠山昌則]
通讯作者:
畠山昌則
Dephosphorylated parafibromin is a transcriptional coactivator of the Wnt/Hedgehog/Notch pathways.
去磷酸化的parafibromin是Wnt/HedgeHog/Notch途径的转录共激活因子。
DOI:
10.1038/ncomms12887
发表时间:
2016-09-21
期刊:
NATURE COMMUNICATIONS
影响因子:
16.6
作者:
[Kikuchi, Ippei, Takahashi-Kanemitsu, Atsushi, Sakiyama, Natsuki, Tang, Chao, Tang, Pei-Jung, Noda, Saori, Nakao, Kazuki, Kassai, Hidetoshi, Sato, Toshiro, Aiba, Atsu, Hatakeyama, Masanori]
通讯作者:
Hatakeyama, Masanori
Parafibromin acts as a signaling hub that orchestrates the Wnt, Hedgehog and Notch signaling pathways
副纤维蛋白充当协调 Wnt、Hedgehog 和 Notch 信号通路的信号中枢
DOI:
--
发表时间:
2015
期刊:
影响因子:
--
作者:
[菊地逸平, 高橋昌史, 野嶋奈津紀, 畠山昌則]
通讯作者:
畠山昌則
Parafibromin転写足場タンパク質機能のリン酸化依存的制御
副纤维蛋白转录支架蛋白功能的磷酸化依赖性调节
DOI:
--
发表时间:
2016
期刊:
影响因子:
--
作者:
[菊地逸平, 高橋昌史, 畠山昌則]
通讯作者:
畠山昌則
共 6 条
Assessment of environmental radioactive contamination using teeth
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批准号:16K15849
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.16万
-
财政年份:2016
-
负责人:TAKAHASHI Atsushi
-
依托单位:
Screening for individual internal exposure using teeth
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批准号:15H05055
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.23万
-
财政年份:2015
-
负责人:TAKAHASHI Atsushi
-
依托单位:
Measurement of low-dose and long-time external exposure using human teeth.
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批准号:26670898
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.33万
-
财政年份:2014
-
负责人:TAKAHASHI Atsushi
-
依托单位:
Investigation of the Roles of Dephosphorylated Parafibromin by SHP2 in Oncogenesis
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批准号:24700965
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项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.83万
-
财政年份:2012
-
负责人:TAKAHASHI Atsushi
-
依托单位:
Improvement effects of chronic administration of carbamazepine on bone metabolism in growing rats.
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批准号:23792499
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项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$2.41万
-
财政年份:2011
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负责人:TAKAHASHI Atsushi
-
依托单位:
Effect of panretinal photocoagulation on ocular blood flow in patients with dabetic retinopathy
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批准号:22791647
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项目类别:Grant-in-Aid for Young Scientists (B)
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资助金额:$1.66万
-
财政年份:2010
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负责人:TAKAHASHI Atsushi
-
依托单位:
Effects of sex hormones on the pathogenesis of nonalcoholic steatohepatitis (NASH)
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批准号:21790678
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项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$1.16万
-
财政年份:2009
-
负责人:TAKAHASHI Atsushi
-
依托单位:
A trial for the improvement of the result of esophageal cancer surgery by molecular chaperone HSP overexpression
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批准号:21591690
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.83万
-
财政年份:2009
-
负责人:TAKAHASHI Atsushi
-
依托单位:
On Establishment of General Synchronous Circuit Design Methodology to Enhance Delay Variation Robustness
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批准号:21300012
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$6.66万
-
财政年份:2009
-
负责人:TAKAHASHI Atsushi
-
依托单位:
Homological Mirror Symmetry of Isolated Hypersurface Singularities With Group Actions
-
批准号:20684003
-
项目类别:Grant-in-Aid for Young Scientists (A)
-
资助金额:$10.82万
-
财政年份:2008
-
负责人:TAKAHASHI Atsushi
-
依托单位:
Effects of carbamazepine on bone metabolism
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批准号:19791630
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项目类别:Grant-in-Aid for Young Scientists (B)
-
资助金额:$1.27万
-
财政年份:2007
-
负责人:TAKAHASHI Atsushi
-
依托单位:
Aconstruction of a routing synthesis system for VLSI packages
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批准号:18500034
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.53万
-
财政年份:2006
-
负责人:TAKAHASHI Atsushi
-
依托单位:
Immune regulation for renal cell carcinoma
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批准号:12671548
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.92万
-
财政年份:2000
-
负责人:TAKAHASHI Atsushi
-
依托单位:
Freshly isolated renal cells as a experimental model system for studying the chemically induced renal injury.
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批准号:59480124
-
项目类别:Grant-in-Aid for General Scientific Research (B)
-
资助金额:$4.35万
-
财政年份:1984
-
负责人:TAKAHASHI Atsushi
-
依托单位:
海外基金