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Novel Vitamin E Analogues with Enhanced Specificity for Malignant Cells

Novel Vitamin E Analogues with Enhanced Specificity for Malignant Cells
新型维生素 E 类似物对恶性细胞具有增强的特异性
批准号:
DP0453372
负责人:
Prof Jiri Neuzil
金额:
$14.56万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Discovery Projects
财政年份:
2004
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2004-01-01 至 2007-12-31

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中文摘要
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英文摘要
The aim of this project is to synthesise and characterise novel compounds based on vitamin E succinate that are capable of efficiently and selectively killing cancer cells. The new compounds will be tested for their ability to induce programmed cell death in cancer cells and the most active of them will be also tested for anti-cancer effect in a pre-clinical model. We believe that novel analogues based on vitamin E succinate can lead to the discovery of very effcient and selective anti-cancer drugs with no side-effects that may be used for patient treatment in the future. This makes our project of exceptional significance.
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