AIDE – Design of aggregation-induced dually emissive bichromophores

AIDE â 聚集诱导的双发射双色团的设计

• 批准号: 514325441
• 负责人: Professor Dr. Thomas J. J. Müller
• 金额: --
• 依托单位: Institut für Theoretische Chemie
• 依托单位国家: 德国
• 项目类别: Research Grants
• 资助国家: 德国
• 项目状态: 未结题
• 来源: https://gepris.dfg.de/gepris/projekt/514325441?language=en
• 关键词: AIDE; Design; aggregation; induced; dually

The aim of this project is the development of non-ionic bichromophoremitters with a dual emission or an environment-sensitive mixed color emission. Therefore, the diversity-oriented synthesis of novel bichromophore libraries is conceived and the systematic determination of molecular structural parameters of aggregation-induced dual emission (AIDE) of bichromophores constituted of diversely substituted merocyanines and triarylamines is studied by optical spectroscopy in solution, in particle systems and crystalline solids, assisted by quantum chemical modeling. Bichromophore emitters are envisioned showing environmental changes from aprotic vs protic or polar vs apolar by occurrence of mixed color emission that can be spectroscopically monitored.Two covalently bound emissive chromophores (donor: UV/vis-absorbing, blue emission; acceptor: red-shifted absorption, long wavelength emission) are placed within a Förster radius in a way that upon spectral overlap of the donor's emission band and the acceptor's absorp-tion band enables an energy transfer from „blue“ donor to „red“ acceptor. The red acceptor will be chosen such that its emission can be distinctly increased upon aggregation in solvent mixtures with variable polarity and/or proticity. The resulting emission color of these Bichromophore systems can be tuned by the efficiency of the energy transfer between donor and acceptor and by the efficiency of the acceptor's emission in dependence of its degree of aggregation. Therefore, partial energy transfer and aggregation-induced emission (AIE) of the acceptor are the prerequisites for the desired dual emission contributed by both donor and acceptor. The envisioned goals A) methodological development of the synthesis strategy for AIE-AIDE bichromophore systemsB) spectroscopic identification of merocyanine-based structures with particularly pronounced AIE properties of the acceptor and AIDE properties of the bichromophor system and the relevant molecular masses/environmental parameters such as polarity and viscosity and the temperature dependence of these influences; detailed investigations of the mechanism of the AIDE on selected bichromophores using spectroscopic methods such as time-resolved emission measurements (ps to ns range) and customer-based modelling (QM/MM treatment based on crystal structure analyses)C) mechanistic rationalization of the underlying energy transfer processesD) strategies for stabilization of bichromophore-based aggregates and preparation and characterization of water dispersible bichromophore nanoparticles E) aggregation studies on particle surfaces for prediction of the optical properties of markers on the basis of AIE-AIDE bichromophoreswill be achieved in synergetic collaboration between organic synthesis, physical organic chemistry and optical spectroscopy.

该项目的目的是开发具有双重发射或对环境敏感的混合颜色排放的非离子双子动物。因此，构思的新型双偶联库文库的多样性综合是由量子系统固定在粒子系统中，在量子上固定在量子上，对多样化替代的梅罗基氨酸和三级疗法对多样取代的梅罗基氨酸和三级疗法进行了系统确定的双孔噬菌体的分子结构参数（辅助）。通过发生混合颜色发射，可以通过光谱监测双纹状体发射器，从而显示出与质子与极性与极性相反的环境变化。两个共价结合的发射色流量（供体：UV/Vis-Absorming，蓝色发射；受体：红移的浮雕，长波长发射）以供体的发射带的光谱重叠和受体的吸收率带来的吸收率带来的能量转移的方式以一种方式，将其放置在förster半径内。将选择红色受体，以使其发射在具有可变的极性和/或原始性的溶剂混合物中可以明显增加。这些双锥团系统的发射颜色可以通过供体和受体之间的能量转移的效率以及受体发射的效率来调节，从而依赖于其聚合程度。因此，受体的部分能量转移和汇总诱导的排放（AIE）是供体和受体贡献所需的双重排放的先决条件。设想的目标a）aie-aide双偶体寄流系统的合成策略的方法论发展，基于梅胶质氨基的结构的光谱鉴定具有尤其明显的受体和辅助性能的AIE特性，以及相关的分子质量/环境参数，例如极性和粘度和粘度的相关质量和环境参数，使用光谱方法（例如，基于晶体结构分析的基于晶体结构分析）的辅助方法（PS至NS范围）和基于客户的建模（QM/mm处理）c）辅助测量方法（QM/mm处理）c）机械稳定性的稳定性和稳定性的稳定性策略的机械化，详细的投资（诸如时期分解的排放测量（PS至NS范围））和基于客户的建模（QM/mm处理）的详细投资（QM/mm处理）双孔小子纳米颗粒E）在颗粒表面上的聚集研究，以预测标记的光学特性，基于AIE-AIDE双孔小子，将在有机合成，物理有机化学和光谱光谱学之间的协同协作中实现。