Sensor development and multi-sensorial control for batch suspension crystallization

批量悬浮结晶的传感器开发和多感官控制

• 批准号: 517791283
• 负责人: Professor Dr.-Ing. Heiko Briesen
• 金额: --
• 依托单位: Lehrstuhl für Systemverfahrenstechnik
• 依托单位国家: 德国
• 项目类别: Research Grants
• 资助国家: 德国
• 项目状态: 未结题
• 来源: https://gepris.dfg.de/gepris/projekt/517791283?language=en
• 关键词: Sensor; development; multi; sensorial; control

Product properties in suspension crystallization processes are notoriously difficult to control for the following basic reasons: (i) the complex underlying physics makes mono-causal feedback control targeting product quality very difficult. (ii) the scarcity of suitable sensors hinders monitoring the full control-relevant process state. The main objective of the project is to establish a holistic model-based multivariable control strategy for suspension crystallization. In the course of the project two novel sensor types will be developed: (i) Electrical impedance spectroscopy shall be established as a multipurpose sensor making total solid concentration and several dissolved compounds accessible with one measurement. (ii) Direct single crystal growth rate monitoring will be established giving access to growth rate without the necessity of any concentration information. Additionally, direct single crystal growth rate monitoring will be tested for being capable to act as a currently non-existent crystal purity sensor. Both sensors will be integrated in a multi-sensorial model-based control approach. The underlying population balance model will be identified online using the available sensors.

由于以下基本原因，悬浮结晶过程中的产品特性非常难以控制：(i)复杂的底层物理使得针对产品质量的单因果反馈控制非常困难。（ii）缺乏合适的传感器阻碍了对与控制相关的过程状态的全面监控。本课题的主要目标是建立一种基于整体模型的悬浮液结晶多变量控制策略。在项目过程中，将开发两种新型传感器：(i)将建立电阻抗谱作为一种多用途传感器，使总固体浓度和几种溶解化合物通过一次测量即可获得。（ii）建立单晶生长速率直接监测，无需任何浓度信息即可获得生长速率。此外，将测试直接单晶生长速率监测是否能够作为目前不存在的晶体纯度传感器。这两个传感器将集成在一个基于多传感器模型的控制方法中。潜在的人口平衡模型将使用可用的传感器在线识别。