ADDING OF CONTROLLED RELEASE OF FLUORIDE FROM RESINOUS MATERIALS BY MICRO-CAPSULATION OF FLUORIDE ADDITIVES

在树脂材料中加入在水中具有较高溶解度的氟化物，可使材料释放大量的氟化物。然而，氟源在早期被全部消耗，材料很快就完成了氟离子的释放。因此，在氟化物表面涂覆疏水薄膜可能会在一定程度上阻止氟与水的接触，导致氟的缓慢释放。在本研究中，我们研究了氟疏水薄膜涂层对树脂材料释氟行为的影响。由于氟化钠的疏水性，用硅烷偶联剂γ-MPTS对其进行处理。XPS分析表明，通过硅烷偶联剂的处理，氟化物表面覆盖了硅醇基之间缩合反应形成的硅氧烷薄膜。经硅烷处理的氟化钠树脂初期的氟化物释放量低于未处理的氟化物树脂。尽管含有硅烷处理的氟化物的树脂继续释放它。此外，经硅烷处理的氟化物树脂与未处理的氟化物树脂一样具有抑制继发性龋齿的作用。这些结果表明，添加硅烷包覆的氟化物添加剂可以实现树脂材料中氟化物的持续释放。

When fluoride with high solubility in water was added into resinous materials, the materials could release large amount of fluoride. However, all of fluoride source was consumed in early stage and the materials finish to release fluoride ion soon. Therefore, the coating of the fluoride with hydrophobic film may prohibit somewhat the contact of fluoride with water diffusing into the resinous material, resulting in slow-releasing of fluoride.In this study, we investigated the effect of the coating of the fluoride with hydrophobic film on fluoride-releasing behavior of the resinous materials. The sodium fluoride was treated with a silane coupling agent, γ-MPTS, because of its hydrophobic property. XPS analysis revealed that the surface of fluoride was coated with siloxane films, which were formed by condensation reactions between silanol groups, by the treatment of a silane coupling agent. The amount of fluoride released from the resin containing silane-treated sodium fluoride was lower than that containing untreated fluoride at the initial stage. Although the resin containing silane-treated fluoride continued to release it. Moreover, the resin containing silane-treated fluoride presented the inhibitory effects of secondary caries as that containing untreated fluoride. These results indicated that the continuous release of fluoride from the resinous materials was acquired by adding of silane-coated fluoride additives.