Insights into pacemaker mechanisms for human stem cell-derived cardiomyocytes with application to biological pacemaker engineering
Insights into pacemaker mechanisms for human stem cell-derived cardiomyocytes with application to biological pacemaker engineering
批准号:
26460303
负责人:
KURATA Yasutaka
金额:
$3.16万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2014
资助国家:
日本
项目状态:
已结题
起止时间:
2014-04-01 至 2017-03-31
中文摘要
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英文摘要
期刊论文(11)
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Distinct dynamical mechanisms underlie the development of phase 2 early afterdepolarizations in human ventricular myocyte models for long QT syndromes
长 QT 综合征的人心室肌细胞模型中 2 期早期后除极发展的不同动力学机制
DOI:
--
发表时间:
2017
期刊:
影响因子:
--
作者:
[Kurata Y, Tsumoto K, Hisatome I, Tanida M, Kuda Y, Shibamoto T]
通讯作者:
Shibamoto T
Distinct mechanisms underlie phase 2 early afterdepolarizations in human ventricular myocyte models of long QT syndromes
长 QT 综合征的人心室肌细胞模型中 2 期早期后除极的不同机制
DOI:
--
发表时间:
2016
期刊:
影响因子:
--
作者:
[Kurata Y, Hisatome I]
通讯作者:
Hisatome I
ヒト心室筋細胞モデルにおける早期後脱分極の再現性とその非線形力学的機序
人心室肌细胞模型中早期后除极的再现性及其非线性机械机制
DOI:
--
发表时间:
2016
期刊:
影响因子:
--
作者:
[倉田康孝, 谷田 守, 九田裕一, 久留一郎, 芝本利重]
通讯作者:
芝本利重
Electrophysiological properties of iPS cell-derived cardiomyocytes from a patient with long QT syndrome type 1 harboring a novel mutation of KCNQ1
来自携带 KCNQ1 新突变的 1 型长 QT 综合征患者的 iPS 细胞来源的心肌细胞的电生理特性
DOI:
--
发表时间:
2015
期刊:
影响因子:
--
作者:
[Kurata Y, Li P, Morikawa K, Miake J, Yamamoto K, Shirayoshi Y, Hisatome I]
通讯作者:
Hisatome I
Dynamical mechanisms of early afterdepolarizations in long QT syndromes: Insights from slow-fast decomposition analyses for human ventricular myocyte models
长QT综合征早期后除极的动力学机制:人心室肌细胞模型慢-快分解分析的见解
DOI:
--
发表时间:
2015
期刊:
影响因子:
--
作者:
[倉田康孝, 谷田 守, 九田裕一, 久留一郎, 芝本利重]
通讯作者:
芝本利重
共 10 条
Theoretical and experimental study of controlling cardiac cell system dynamics using HL-1 mouse cardiomyocytes and a mathematical model
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批准号:19K07290
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项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.75万
-
财政年份:2019
-
负责人:KURATA Yasutaka
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依托单位:
Development of novel mathematical models for human cardiac myocytes based on bifurcation analysis and comparative study
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批准号:23590266
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.24万
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财政年份:2011
-
负责人:KURATA Yasutaka
-
依托单位:
Dynamical properties of mouse ES-cell derived cardiomyocytes during differentiation: insights from bifurcation analysis based on nonlinear dynamical system theory
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批准号:20590220
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.0万
-
财政年份:2008
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负责人:KURATA Yasutaka
-
依托单位:
Dynamical mechanisms of pacemaker generation in cardiac myocytes: a comprehensive study based on bifurcation theory with application to biological pacemaker engineering
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批准号:17590192
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.66万
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财政年份:2005
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负责人:KURATA Yasutaka
-
依托单位:
Development of a novel thermodynamical model for sinoatrial node pacemaker cells and bifurcation analysis of the model systems in terms of nonlinear dynamics.
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批准号:15590195
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.47万
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财政年份:2003
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负责人:KURATA Yasutaka
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依托单位:
海外基金