Development of a novel biodegradable ophthalmic biomaterial based on porous silicon

在这个跨学科的项目中，我们将联合收割机结合我们的不同专业知识，开发用于控制可生物降解支架材料上干细胞行为的前沿技术。我们将开发一种新的眼科生物植入物从多孔硅使用形貌和化学方面的表面改性以及固定和/或纳入生物活性物质，如生长因子，以允许哺乳动物干细胞的生长和分化。该项目将产生用于治疗致盲性眼病的生物材料。植入利姆布斯，生物植入物可以改善一些常见的角膜疾病。

Within this interdisciplinary project, we will combine our diverse expertise towards the development of frontier technologies for control of stem cell behaviour on biodegradable scaffold materials. We will develop a novel ophthalmic bioimplant from porous silicon using topographical and chemical aspects of surface modification as well as immobilisation and/or incorporation of bioactive species such as growth factors, to permit the growth and differentiation of mammalian stem cells. This project will result in biomaterials for the treatment of blinding diseases of the eye. Implanted into the limbus, bioimplants may ameliorate some common corneal diseases.