Building bio-inspired smart nanochannels for virus detection

构建用于病毒检测的仿生智能纳米通道

• 批准号: DP160104362
• 负责人: Prof Nicolas Voelcker
• 金额: $ 32.34万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP160104362
• 关键词: Building; bio; inspired; smart; nanochannels

This project aims to harness high-precision silicon nanofabrication methods to create the next generation of bio-inspired viral biosensors. The new technology would enable prompt, cost-efficient, and accurate detection of virus contamination of our water and food supplies. The project plans to fabricate arrays of parallel double-layered nanochannels in silicon via templated etching, with surface functionalisation to display receptors. These nanochannels are designed to act as size-selective filters for electrochemical and electrochemiluminescence sensing. The project plans to explore innovative signal amplification and multiplexing capabilities for ultrasensitive detection of norovirus and bacteriophages.

该项目旨在利用高精度硅纳米纤维方法来创建下一代生物启发的病毒生物传感器。这项新技术将使我们能够迅速、经济、准确地检测我们的水和食品供应中的病毒污染。该项目计划通过模板蚀刻在硅中制造平行的双层纳米通道阵列，表面功能化以显示受体。这些纳米通道被设计成用作电化学和电化学发光传感的尺寸选择性过滤器。该项目计划探索创新的信号放大和多路复用能力，用于诺如病毒和噬菌体的超灵敏检测。