Micro/nano smart surfaces to unlock the potential of multipotent stem cells

该项目旨在确定微/纳米结构对干细胞机械转导的相互作用，并控制细胞环境。预计这将扩大我们对如何控制干细胞命运的了解。预期成果是用于微/纳米结构和智能表面的新型可扩展技术，受控干细胞扩增和分化，以及基于细胞相互作用创建蛋白质表达库。这些结果将为未来开发具有指导意义的生物材料以驱动干细胞扩增和组织再生提供关键信息。这些材料应该有利于未来开发高效和具有成本效益的再生医学解决方案。

This project aims to determine the interplay of micro/nanostructures on stem cell mechanotransduction and to control the cellular environment. It is expected that this will expand our knowledge on how to control stem cell fate. Expected outcomes are novel scalable technologies for micro/nanostructures and smart surfaces, controlled stem-cell expansion and differentiation, and the creation of a library of protein expression based on the cell interactions. These outcomes will provide critical information required for the future development of instructive biomaterials to drive stem cell expansion and tissue-regeneration. Those materials should benefit the future development of efficient and cost-effective regenerative medicine solutions.