The development of tyrosine kinase inhibitors for the treatment of inflammation and malignant disease.
The development of tyrosine kinase inhibitors for the treatment of inflammation and malignant disease.
批准号:
LP0454363
负责人:
Prof David Hume
金额:
$18.8万
依托单位国家:
澳大利亚
项目类别:
Linkage Projects
财政年份:
2004
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2004-08-31 至 2007-08-30
中文摘要
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英文摘要
Through the combination of expertise from the Industry partner and the Hume group this project aims to develop specific inhibitors of the CSF-1 receptor protein tyrosine kinase in order to demonstrate their efficacy as modulators of CSF-1 dependent macrophage and tumour cell function in vitro. The expected outcome will be a lead set of targets which can be further assessed for therapeutic potential in clinical trials.
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会议论文
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负责人:Prof David Hume
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财政年份:2004
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负责人:Prof David Hume
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依托单位:
Molecular genetics of macrophage activation.
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资助金额:$28.36万
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财政年份:2003
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负责人:Prof David Hume
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Gene Expression Profiling and de novo Transcriptome Sequencing using Geneballs
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批准号:LP0349397
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财政年份:2003
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负责人:Prof David Hume
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依托单位:
Transcriptional regulation of the c-fms (CSF-1R) gene in macrophages.
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财政年份:2002
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负责人:Prof David Hume
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依托单位:
The role of the microphthalmia transcription factor family in macrophage differentiation.
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财政年份:2001
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Mechanisms of macrophage activation by immunostimulatory DNA
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负责人:Prof David Hume
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依托单位:
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资助金额:$20.43万
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财政年份:1998
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负责人:Prof David Hume
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依托单位:
国内基金
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依托单位: