Synthesis of Highly Selective Polymer Materials with Solid-Solution Phases and Multiphase-Structure Analysis under Functioning State

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Dextran-type polysaccharides containing sulfamide and sulfate groups at regio-selective positions were synthesized by a series of reactions starting from the ring-opening polymerization of 1,6-anhydro-azido sugars. The sulfamide group exhibted almost the same anticoagulant activity as that of the sulfate group, and the former had a function to decrease the acute toxicity <LD_(50)> . 1,5- <alpha> -Linked furanan-type polysaccharides which were prepared by the ring-opening polymerization of 1,4-anhydro-ribose and -xylose were sulfated to give sulfated furanan-type polysaccharides. These heparinoids showed the highest anticoagulant activity of the so-far prepared heparinoids. The structure analysis of synthetic polysaccharides and sulfated ones was performed by using ordinary NMR and 2D NMR spectroscopy as well as the elemental analysis, indicating the position of sulfate group.Chloromethylated polystyrene beads were reacted with various alkylamines to provide the stationary phase of high … More perfomance liquid chromatography. The obtained chloromethylated polystyrene beads can be used in a wide pH range. In addition, the selective separation of halobenzenes and alkylbenzenes was possible by properly choosing the alkyl chain length, for example, by using a <C_(14)> stationary phase. Functionalization of crosslinked poly(chloromethylstyrene) beads was carried out by the reaction with sodium nitrite in the presence of phase transfer catalyst to afford the beads having carboxyl and hydroxyl groups.Thermotropic aromatic polyesters and low-molecular-weight model compounds were synthesized. They consisted of aromatic mesogens and flexible alkylene spacers. The structure of aromatic polyesters most of which were hardly soluble in solvents were analyzed with solid state CP/MAS <^(13)C> NMR spectroscopy. In the polyester prepared at low temperature, the alkoxy group bonded to the aromatic ring had a fixed orientation, which provides a guide to the molecular design of liquid crystalline polymers with excellent mechanical properties. Less