Thrombosis due to dysfunction of anticoagulant activity and strategy for prevention of thrombosis
Thrombosis due to dysfunction of anticoagulant activity and strategy for prevention of thrombosis
批准号:
20390278
负责人:
MIYATA Toshiyuki
金额:
$11.98万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2011
中文摘要
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英文摘要
We have performed the genetic analysis in 173 Japanese patients with venous thromboembolism(VTE) and identified nonsynonymous mutations in 55 patients. We also performed genetic analysis in 18 pregnant women with VTE and identified the mutations in 5 patients. We estimated the frequency of hereditary deficiency of ADAMTS13. We determined the crystal structure of the ADAMTS13-DTCS domain.
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プロテインS欠損症:国立循環器病センターでの研究、血栓性素因部会「血栓性素因・プロテインS欠乏症/欠損症をめぐる最近の話題」
蛋白质 S 缺乏症:国家脑心血管中心血栓易感性小组委员会的研究“围绕血栓易感性/蛋白质 S 缺乏/缺乏的最新主题”
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[高久史麿, 他, 千原和夫, 宮田敏行]
通讯作者:
宮田敏行
DOI:
10.1182/blood-2008-07-169359
发表时间:
2009-05-21
期刊:
BLOOD
影响因子:
20.3
作者:
[Banno, Fumiaki, Chauhan, Anil K., Miyata, Toshiyuki]
通讯作者:
Miyata, Toshiyuki
Imaging analysis of platelet thrombus formation in Adamts 13-mutant mice.
Adamts 13 突变小鼠血小板血栓形成的成像分析。
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Fumiaki Banno, 他6名]
通讯作者:
他6名
シンポジウム4「血栓止血・血管生物学」Thrombosis and hemostasis/vascular biology,静脈血栓塞栓症の遺伝的素因、Genetic risk factor for thrombophilia
研讨会 4:血栓形成与止血/血管生物学、血栓形成倾向的遗传危险因素
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[Tamagawa-Mineoka R, et al., 宮田敏行]
通讯作者:
宮田敏行
「遺伝子改変血栓症モデル」疾患モデルの作製と利用-循環器疾患(北徹・堀内久徳・柳田素子・猪原匡史・冨本秀和・並河徹編集)
《转基因血栓模型》疾病模型的创建和使用 - 心血管疾病(作者:Toru Kita、Hisanori Horiuchi、Motoko Yanagita、Tadashi Inohara、Hidekazu Tomimoto、Toru Namikawa)
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[宮田敏行, 水口純, 坂野史明]
通讯作者:
坂野史明
共 37 条
Genetic background of thrombophilia using third generation DNA sequencing
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批准号:19K08875
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.75万
-
财政年份:2019
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负责人:MIYATA Toshiyuki
-
依托单位:
Production and analysis of Adamts13-Bac-TRAP mice that express fluorescent protein EGFP driven by Adamts13 promoter
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批准号:23659494
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.33万
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财政年份:2011
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负责人:MIYATA Toshiyuki
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依托单位:
A Comprehensive Study of Production, Rice milling, Export and Consumption of Thai Jasmine Rice
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批准号:18530197
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.68万
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财政年份:2006
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负责人:MIYATA Toshiyuki
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依托单位:
Studies on causative gene for thrombotic thrombocytopenic purpura, ADAMTS13
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批准号:17390285
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.51万
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财政年份:2005
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负责人:MIYATA Toshiyuki
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依托单位:
Functional analysis of endoplasmic reticulum stress-induced genes, NDRG1 and HERPUD1
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批准号:15570107
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.37万
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财政年份:2003
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负责人:MIYATA Toshiyuki
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依托单位:
Political Economy of Thai "Jasmine" Rice
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批准号:15530201
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.09万
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财政年份:2003
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负责人:MIYATA Toshiyuki
-
依托单位:
Studies on genes involved in endothelial dysfunction involved in thrombosis and atherosclerosis
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批准号:10044337
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项目类别:Grant-in-Aid for Scientific Research (B).
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资助金额:$4.16万
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财政年份:1998
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负责人:MIYATA Toshiyuki
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依托单位:
Studies on new proteins involved in vascular endothelial injury
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批准号:09680607
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.86万
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财政年份:1997
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负责人:MIYATA Toshiyuki
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依托单位:
Studies on genes involved in thrombois on endothelial cells
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批准号:08044333
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项目类别:Grant-in-Aid for international Scientific Research
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资助金额:$4.67万
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财政年份:1996
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负责人:MIYATA Toshiyuki
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依托单位:
Studies on the initiation of extrinsic blood coagulation reaction
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批准号:07680665
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$1.47万
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财政年份:1995
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负责人:MIYATA Toshiyuki
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依托单位:
New and rapid diagnostic method for cardiovascular disease and prothrombotic state
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批准号:06557063
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项目类别:Grant-in-Aid for Developmental Scientific Research (B)
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资助金额:$4.54万
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财政年份:1994
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负责人:MIYATA Toshiyuki
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依托单位:
Three-Dimensional Structure of Human Tissue Factor
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批准号:05680539
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.34万
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财政年份:1993
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负责人:MIYATA Toshiyuki
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依托单位:
Study on the extrinsic blood coagulation
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批准号:03680151
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.22万
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财政年份:1991
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负责人:MIYATA Toshiyuki
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依托单位:
Structural Studies on Functional Abnormality of Fibrinogen and Factor IX
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批准号:01571236
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.34万
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财政年份:1989
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负责人:MIYATA Toshiyuki
-
依托单位:
海外基金