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Physiological and morphological studies on microcirculation of the eye during accommodation

调节过程中眼微循环的生理和形态学研究

基本信息

批准号：
60440080
负责人：
TOKORO Takashi
金额：
$ 10.5万
依托单位：
Tokyo Medical and Dental University
依托单位国家：
日本
项目类别：
Grant-in-Aid for General Scientific Research (A)
财政年份：
1985
资助国家：
日本
起止时间：
1985 至 1987
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-60440080/
关键词：
Scanning electron microscopy Microcirculation of the eye Aqueous outflow Infusion method of plastic material ciliary body accommodation 赤外線ファコメータ虹彩樹脂注入法

项目摘要

1. We examined the three-dimentional structure of the ciliary vessels and of the outflow routes for aqueous humor in cynomolgus monkeys with the corrosion cast technique and scanning electron microscopy.(1) Arterial supply of the ciliary body had two pathways which were the long posterior and the anterior ciliary arteries, but no venous drainage system was seen without the vortex system. The collector channeles of Schlemm's canal had no communication with the ciliary circulation.(2) The casting material infused into the anterior chamber, the method of which was developed by ourselves, was filled in the main and the uveoscleral routes.In the uveoscleral outflow, the cast reached to suprachoroidal space passing through the trabecular meshwork, the ciliary muscle space, small pores in the ciliary muscle bundles and the supraciliary space.(3) The pores in the ciliary muscle bundles became narrowing after instillation of atropine (accommodation relaxation) or ilocarpine (accommodation spasm).2. Relationship between the microfluctuation of accommodation in the human eyeby an infrared optometer and the pulsatiion of heart was found. Using the samemethod, accommodation of the myopia was measured. As the results, the accommodative responses of the corrected myopia by spectacles were smaller than those ofemmetropia.

1.本文用铸型技术和扫描电镜观察了食蟹猴睫状血管的三维结构和房水的流出途径。(1)睫状体的动脉供应有睫状体长后动脉和睫状体前动脉两条途径，但无静脉引流系统，无漩涡系统。Schlemm管的收集沟与睫状循环不相通。(2)采用自行研制的前房铸型材料注入方法，在主路和葡萄膜巩膜路注入铸型材料，在葡萄膜巩膜流出路，铸型材料经小梁网、睫状肌间隙、睫状肌束小孔及睫状体上间隙到达脉络膜上腔。(3)滴注阿托品（调节松弛）或伊洛卡品（调节痉挛）后，睫状肌束孔变窄.本文用红外线验光仪测量了人眼调节的微波动与心脏搏动之间的关系，并用同样的方法测量了近视眼的调节。结果表明，眼镜矫正近视眼的屈光反应小于正视眼。