The molecular blue-print for a mitochondrial nanomachine

线粒体纳米机器的分子蓝图

• 批准号: DP160100227
• 负责人: Prof Trevor Lithgow
• 金额: $ 35.97万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2016
• 资助国家: 澳大利亚
• 起止时间: 2016-01-01 至 2019-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP160100227
• 关键词: molecular; blue; print; mitochondrial; nanomachine

The objective of the project is to develop a comprehensive understanding of the architecture of a biological nanomachine through broad-reaching investigation of the molecular contacts that enable the component parts to work together. The project plans to take the foundation knowledge of each of the component parts and build a conceptual framework of engineering principles to understand how the nanomachine is assembled, using a breakthrough technology to address the precise architecture of the component parts within the nanomachine.

该项目的目标是通过对使组成部分能够共同工作的分子接触进行广泛的调查，全面了解生物纳米机器的结构。该项目计划采用每个组成部分的基础知识，并建立一个工程原理的概念框架，以了解纳米机器是如何组装的，使用突破性技术来解决纳米机器内组成部分的精确架构。