Investigation of the molecular machinery enabling phage to enter bacteria.

研究使噬菌体进入细菌的分子机制。

• 批准号: DP220100338
• 负责人: Prof Trevor Lithgow
• 金额: $ 41.27万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2022
• 资助国家: 澳大利亚
• 起止时间: 2022-03-01 至 2025-02-28
• 项目状态: 未结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP220100338
• 关键词: Investigation; molecular; machinery; enabling; phage

This project aims at a comprehensive understanding of the architecture of a biological nanomachine, called a phage, through broad-reaching investigation into how the component parts to work together to function in attacking bacteria. The discovery project takes the foundation knowledge of each of the component parts, builds a conceptual framework using breakthrough technology to address the precise architecture of the component parts within the nanomachine. The project aims to expand Australia’s knowledge base and research capability in the research frontier of nanomachines. This ground-breaking research program provides unique training opportunities for research students and staff in projects driving frontier technology applications.

该项目旨在通过广泛的研究组件如何共同起作用以在攻击细菌中起作用，旨在全面了解生物纳米机器（称为噬菌体）的结构。 Discovery项目掌握了每个组件部分的基础知识，使用突破性技术构建了一个概念框架，以解决纳米机械中组件部分的精确体系结构。该项目旨在扩大澳大利亚在纳米机器研究边界的知识库和研究能力。这项开创性的研究计划为研究学生和员工提供了独特的培训机会，以推动前沿技术应用程序。