Investigation of the molecular machinery enabling phage to enter bacteria.

研究使噬菌体进入细菌的分子机制。

• 批准号: DP220100338
• 负责人: Prof Trevor Lithgow
• 金额: $ 41.27万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2022
• 资助国家: 澳大利亚
• 起止时间: 2022-03-01 至 2025-02-28
• 项目状态: 未结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP220100338
• 关键词: Investigation; molecular; machinery; enabling; phage

This project aims at a comprehensive understanding of the architecture of a biological nanomachine, called a phage, through broad-reaching investigation into how the component parts to work together to function in attacking bacteria. The discovery project takes the foundation knowledge of each of the component parts, builds a conceptual framework using breakthrough technology to address the precise architecture of the component parts within the nanomachine. The project aims to expand Australia’s knowledge base and research capability in the research frontier of nanomachines. This ground-breaking research program provides unique training opportunities for research students and staff in projects driving frontier technology applications.

该项目旨在通过广泛研究各组成部分如何协同工作来攻击细菌，全面了解一种名为噬菌体的生物纳米机器的结构。该发现项目获取了每个部件的基础知识，使用突破性技术建立了一个概念框架，以解决纳米机器中部件的精确架构。该项目旨在扩大澳大利亚在纳米机器研究前沿领域的知识基础和研究能力。这一开创性的研究计划为研究学生和工作人员提供了独特的培训机会，以推动前沿技术应用的项目。