A Video-Rate Nanoscopy Facility for Super-Resolution Imaging

用于超分辨率成像的视频速率纳米显微镜设备

• 批准号: LE150100110
• 负责人: Prof Trevor Lithgow
• 金额: $ 20万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Linkage Infrastructure, Equipment and Facilities
• 财政年份: 2015
• 资助国家: 澳大利亚
• 起止时间: 2015-01-01 至 2015-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/LE150100110
• 关键词: Video; Rate; Nanoscopy; Facility; Super

A video-rate nanoscopy facility for super-resolution imaging: Super-Resolution Microscopy (SRM) is a major frontier technology and is revolutionising our understanding of the structure and dynamics of cellular organisation. A video-rate SRM imaging facility will be established and is expected to bridge the gap between the functional dynamics and structure of living systems at the level of the single molecule. In leading international centres, breakthroughs are being made in understanding molecular mechanisms in cancer, infectious diseases and neuropathologies. Beyond purely biomedical considerations, SRM is redefining our knowledge of cellular architecture and will impact on our understanding of the fundamental biology of all plants, animals and micro organisms.

用于超分辨率成像的视频速率纳米显微镜设施：超分辨率显微镜（SRM）是一项重大前沿技术，正在彻底改变我们对细胞组织结构和动力学的理解。将建立一个视频速率SRM成像设备，并有望在单分子水平上弥合生命系统的功能动力学和结构之间的差距。在主要的国际中心，在理解癌症、传染病和神经病理学的分子机制方面正在取得突破。除了纯粹的生物医学考虑之外，SRM正在重新定义我们对细胞结构的认识，并将影响我们对所有植物，动物和微生物的基础生物学的理解。