An investigation into flagellotropic bacteriophage stability and biology

促鞭毛噬菌体稳定性和生物学的研究

• 批准号: DP210101126
• 负责人: Prof Trevor Lithgow
• 金额: $ 25万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2021
• 资助国家: 澳大利亚
• 起止时间: 2021-01-01 至 2023-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP210101126
• 关键词: investigation; into; flagellotropic; bacteriophage; stability

This project aims to understand the capabilities of a type of virus called bacteriophage (phage). Significant economic loss in the food industry has led the USA and Europe to deploy phage to decontaminate food-processing machinery. These phage kill food-spoiling bacteria. This project expects to fill gaps in our knowledge, particularly to assit in choosing phage that are of increased stability and thus more long-lasting for deployment in industrial settings, and to inform additives to the phage preparations to increase their potency in killing bacteria. The project should provide significant benefits in training students and staff in methodology for investigating phage for future applications in Australian industry and biotechnology.

该项目旨在了解一种称为噬菌体（噬菌体）的病毒的能力。食品工业的重大经济损失导致美国和欧洲部署噬菌体来净化食品加工机械。这些噬菌体能杀死破坏食物的细菌。该项目预计将填补我们知识的空白，特别是帮助选择具有更高稳定性的噬菌体，从而更持久地用于工业环境中，并为噬菌体制剂提供添加剂，以提高其杀灭细菌的效力。该项目应提供培训的学生和工作人员在方法研究噬菌体在澳大利亚工业和生物技术的未来应用显着的好处。