An investigation into flagellotropic bacteriophage stability and biology

促鞭毛噬菌体稳定性和生物学的研究

• 批准号: DP210101126
• 负责人: Prof Trevor Lithgow
• 金额: $ 25万
• 依托单位: Monash University
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2021
• 资助国家: 澳大利亚
• 起止时间: 2021-01-01 至 2023-12-31
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP210101126
• 关键词: investigation; into; flagellotropic; bacteriophage; stability

This project aims to understand the capabilities of a type of virus called bacteriophage (phage). Significant economic loss in the food industry has led the USA and Europe to deploy phage to decontaminate food-processing machinery. These phage kill food-spoiling bacteria. This project expects to fill gaps in our knowledge, particularly to assit in choosing phage that are of increased stability and thus more long-lasting for deployment in industrial settings, and to inform additives to the phage preparations to increase their potency in killing bacteria. The project should provide significant benefits in training students and staff in methodology for investigating phage for future applications in Australian industry and biotechnology.

该项目旨在了解一种称为噬菌体（噬菌体）的病毒的能力。食品工业的大量经济损失导致美国和欧洲部署噬菌体来净化食品加工机制。这些噬菌体杀死了食物中的细菌。该项目希望填补我们的知识差距，尤其是在选择稳定性增加，从而在工业环境中部署更持久的噬菌体方面，并为噬菌体的准备工作提供了更多的持久，以增加噬菌体的准备，以增加其杀死细菌的效力。该项目应为培训学生和员工的方法学带来重大好处，以调查噬菌体在澳大利亚工业和生物技术中的未来应用。