The endogenous growth and angiogenesis factor in the placenta and the placental bed.
胎盘和胎盘床的内源性生长和血管生成因子。
基本信息
- 批准号:62570747
- 负责人:
- 金额:$ 1.15万
- 依托单位:
- 依托单位国家:日本
- 项目类别:Grant-in-Aid for General Scientific Research (C)
- 财政年份:1987
- 资助国家:日本
- 起止时间:1987 至 1988
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
Rapid neovasculaization (angiogenesis) takes place in the placental bed of the uterus and the placenta during pregnancy. Whereas the structural components of uterine and placental angiogenesis have been studied extensively, the mechanisms by which these new blood vessels arise are still poorly understood. In this study, I have employed in vitro assay to investigate whether these tissues possess growth and angiogenesis activities. The results demonstrate the presence of factors that stimulate prolieration of mouse BALB/C 3T3 cells and cultured bovine capillary endothelial cells. These actieties are present in extracts of myometrium, placental bed and placenta of the pregnant rat as well as human placenta.
在怀孕期间,子宫胎盘床和胎盘会发生快速新生血管形成。虽然子宫和胎盘血管生成的结构成分已经被广泛研究,但这些新血管产生的机制仍然知之甚少。在这项研究中,我采用体外实验来研究这些组织是否具有生长和血管生成活性。结果表明,小鼠BALB/C3T3细胞和培养的牛毛细血管内皮细胞存在促进增殖的因素。这些活性存在于妊娠大鼠的子宫肌层、胎盘床和胎盘以及人胎盘的提取物中。
项目成果
期刊论文数量(11)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Takehiko Yasumizu: Acta Obst Gynaec Jpn. (1989)
安水武彦:Acta Obst Gynaec Jpn.
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
- 作者:
- 通讯作者:
Takehiko Yasumizu; Junzo Kato: "Ovarian growth factor" Obstet. Gynecol. 55. 555-558 (1988)
安水武彦;
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
- 作者:
- 通讯作者:
安水洸彦,加藤順三: 産科と婦人科. 55. 555-558 (1988)
Yasuhiko Yasumi,Junzo Kato:妇产科 55. 555-558 (1988)
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
- 作者:
- 通讯作者:
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YASUMIZU Takehiko其他文献
YASUMIZU Takehiko的其他文献
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{{ truncateString('YASUMIZU Takehiko', 18)}}的其他基金
THE EFFECT OF PREGNANCY,PARTURITION AND LACTATION ON BONE MINERAL METABOLISM IN HEALTHY WOMEN
妊娠、分娩和哺乳期对健康女性骨矿物质代谢的影响
- 批准号:
08671878 - 财政年份:1997
- 资助金额:
$ 1.15万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
Expression and synthesis of basic FGF in the placenta and umbilical vessel : Association with pathogenesis of preeclampsia.
胎盘和脐血管中碱性 FGF 的表达和合成:与先兆子痫发病机制的关联。
- 批准号:
04670994 - 财政年份:1992
- 资助金额:
$ 1.15万 - 项目类别:
Grant-in-Aid for General Scientific Research (C)
Physiological Roles of Basic FGF on the Development of Uteroplacental Circulation
碱性 FGF 对子宫胎盘循环发育的生理作用
- 批准号:
01570922 - 财政年份:1989
- 资助金额:
$ 1.15万 - 项目类别:
Grant-in-Aid for General Scientific Research (C)
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