The endogenous growth and angiogenesis factor in the placenta and the placental bed.

快速的新生血管（血管生成）发生在子宫的胎盘床和胎盘在怀孕期间。虽然子宫和胎盘血管生成的结构成分已经被广泛研究，但这些新血管产生的机制仍然知之甚少。在这项研究中，我采用体外实验来研究这些组织是否具有生长和血管生成活性。结果表明，存在刺激小鼠BALB/C 3T3细胞和培养牛毛细血管内皮细胞增殖的因子。这些活性存在于妊娠大鼠子宫肌层、胎盘床和胎盘以及人胎盘的提取物中。

Rapid neovasculaization (angiogenesis) takes place in the placental bed of the uterus and the placenta during pregnancy. Whereas the structural components of uterine and placental angiogenesis have been studied extensively, the mechanisms by which these new blood vessels arise are still poorly understood. In this study, I have employed in vitro assay to investigate whether these tissues possess growth and angiogenesis activities. The results demonstrate the presence of factors that stimulate prolieration of mouse BALB/C 3T3 cells and cultured bovine capillary endothelial cells. These actieties are present in extracts of myometrium, placental bed and placenta of the pregnant rat as well as human placenta.