Clinico-Pathological Study on Long Junctional Epithelium

长连接上皮的临床病理学研究

• 批准号: 63570892
• 负责人: OGAWA Tetsuji
• 金额: $ 1.34万
• 依托单位: Hiroshima University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for General Scientific Research (C)
• 财政年份: 1988
• 资助国家: 日本
• 起止时间: 1988 至 1989
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-63570892/
• 关键词: Long Junctional Epithelium; Light Microscopy; Electron Microscopy; Periodontal Disease; Epithelial Attachment; long junctional epithelium; light microscopy; electron microscopy; periodontal disease; epithelial attachment; 歯周炎; 結合組織性付着

This study was described the structure and function of long junctional epithelium (LJE) formed on the root surfaces following periodontal surgery.1. Structural Changes of LJE After Plaque InfectionThe materials were premolars of 5 beagle dogs. Plaque accumulation was carried out to the LJE established on the denuded cementum surfaces. It was demonstrated that the findings of destructing LJE and deepening gingival sulcus were same as JE clinically, light and electron microscopycally following plaque infection. It was suggested that LJE was functioned effectively for barrier to the irritant as same as JE.2. Structural changes of LJE after application of irritantsThe materials were rats first molars. Application of PGE_2 (0.5mg/ml) and ET (0.2mg/ml, E. coli) were performed to the LJE established on the denuded dentin surfaces. It was recognized that the findings of destructing LJE and deepening gingival sulcus were as same as JE light and electron microscopycally after applications of PGE_2 and ET. These finding indicated that LJE was functioned effectively for barrier and tissue repair as same as JE.

本研究旨在探讨牙周手术后牙根面长结合上皮的结构和功能.实验材料为5只Beagle犬的前磨牙。对在裸露的牙骨质表面上建立的LJE进行菌斑积累。结果表明，菌斑感染后，LJE破坏、龈沟加深的临床、光镜和电镜表现与JE相同。提示LJE具有与JE相同的抗刺激屏障作用。实验材料为大鼠第一磨牙。应用PGE_2（0.5mg/ml）和ET（0.2mg/ml）对E. coli）对建立在裸露牙本质表面上的LJE进行检测。认为应用PGE_2和ET后，LJE破坏，龈沟加深的光镜和电镜表现与JE相同。这些结果表明，LJE具有与JE相同的屏障和组织修复功能。

项目成果

OGAWA, T., et al: "Hitological study of long junctional epithelium -Electron microscopic findings following plaque accumlations-" J. Japan. Ass. Periodont.33 (2). (1991)

OGAWA, T. 等人：“长交界上皮的组织学研究 - 斑块积聚后的电子显微镜结果 -” J. Japan。

河内 美穂: "Long junctional epitheliumに関する組識学的研究 ーラット裸出象牙質面に対する形成進程についてー" 広島大学歯学雑誌. 22. 217-225 (1990)

Miho Kawachi：“长连接上皮的组织学研究 - 暴露的大鼠牙本质表面的形成过程 -” 广岛大学牙科杂志 22. 217-225 (1990)。

岡本 莫: "歯周病の科学" 医歯薬出版, (1991)

冈本茂：《牙周病的科学》石药出版社，（1991）

河内 美穂: "Long junctional epitheliumに関する組識学的研究 ーその成立と結合組識性再付着の関係についてー" 日本歯周病学会誌. 33. (1991)

Miho Kawachi：“长连接上皮的组织学研究 - 其形成及其与结缔组织再附着的关系 -”日本牙周病学会杂志 33。（1991）

河内美穂: "Long junctional epitheliumに関する組織学的研究-ラット裸出象牙質面に対する形成過程について" 広島大学歯学雑誌. 22. (1990)

Miho Kawachi：“长连接上皮的组织学研究 - 暴露的大鼠牙本质表面的形成过程”广岛大学牙科杂志 22。（1990）