Studies on Application of Shape Memory Alloy Plate for Internal Fixation of Jaws

形状记忆合金板在颌骨内固定中的应用研究

• 批准号: 63870079
• 负责人: SHIODA Shigetoshi
• 金额: $ 4.54万
• 依托单位: Tokyo Medical and Dental University, Faculty of Dentistry
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Developmental Scientific Research (B).
• 财政年份: 1988
• 资助国家: 日本
• 起止时间: 1988 至 1990
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-63870079/
• 关键词: NiーTi alloy; Shape memory effect; Transformation temperature; Heatーtreatment; Tensile test; Compression plate; 張張試験; NiTi合金; 形状記憶合金; 振動減衰能; 衝撃吸収性; 圧迫骨接合副子

Ni-Ti alloy compression mini-plate was developed for rigid boneーfixation in oral surgery. The investigation of the mechanical properties of this plate and the biocompatibility of NiーTi alloy was performed to obtain basic data for its clinical application. Transformation temperatures of the alloys were measured to evaluate the effect of heat-treatment temperatures. Tensile and shape recovery tests were performed on four types of mini-plates, i. e., four-hole regular and long types Ni-49.49Ti (at%), five-hole regular type Ni-49.49Ti (at%), and Ni-49.26Ti (at%).The following results were obtained.1. Specimens with a heat-treatment at 500^ﾟC, for 30 minutes in both compositions showed adequate As points (about 25^ﾟC) and Af points (44-50^ﾟC) for clinical use.2. In the tensile and shape recovery tests, the 500^ﾟC heat-treated four-hole regular type plate showed better mechanical properties than the 440^ﾟC heat-treated one.3. The five-hole regular type plate of Ni-49.49Ti (at%) alloy had the best mechanical properties for clinical application, judging from the amount and the temperature of shape recovery.4. Ni-Ti alloy was evaluated for the biocompatibility by a cell culture method and showed relatively high cell attachment and growth. Its biocompatibility appears to be better than that of Vitellium.5. Ni-Ti and Vitellium showed almost the same tissue response in rats. Tumorigenicity of NiーTi was not always strong, but similar to that of Vittallium.It is concluded that NiーTi shape memory alloy miniーplates should be applied for internal bone ーfixation in oral surgery.

镍钛合金压缩微型接骨板专为口腔手术中的刚性骨固定而开发。对该钢板的力学性能和镍钛合金的生物相容性进行研究，为其临床应用提供基础数据。测量合金的转变温度以评估热处理温度的影响。对四种类型的微型板进行了拉伸和形状恢复测试，即：即四孔规则型和长型Ni-49.49Ti(at%)、五孔规则型Ni-49.49Ti(at%)和Ni-49.26Ti(at%)。获得以下结果： 1．两种组合物在500^ﾟC下热处理30分钟的样品显示出足够的As点（约25^ﾟC）和Af点（44-50^ﾟC）供临床使用。2．在拉伸和形状恢复试验中，500^ﾟC热处理的四孔普通板比440^ﾟC热处理的四孔普通板表现出更好的力学性能。3．从形状恢复量和温度来看，Ni-49.49Ti(at%)合金五孔普通型接骨板具有最佳的临床力学性能。 4．通过细胞培养方法评估镍钛合金的生物相容性，并显示出相对较高的细胞附着和生长。它的生物相容性似乎比 Vitellium 更好。5。 Ni-Ti 和 Vitellium 在大鼠中表现出几乎相同的组织反应。 NiTi的致瘤性并不强，但与Vittallium的致瘤性相似。结论是NiTi形状记忆合金微型钢板应应用于口腔外科骨内固定。

项目成果

冨塚 謙一: "形状記憶合金を応用した顎骨組織内副子の機械的性質に関する研究" 口腔病学会雑誌. 58. 59-73 (1991)

Kenichi Tomizuka：“使用形状记忆合金研究颌骨夹板的机械性能”口腔医学会杂志 58. 59-73 (1991)。

冨塚 謙一,吉増 秀實,田中 信幸,塩入 重彰,塩田 重利,米山 隆之 浜中 人士: "顎矯正手術施行時の顎間固定に用いる超弾性型NiーTi合金ワイヤ-の開発" 日本口腔外科学会雑誌.

Kenichi Tomizuka、Hidemitsu Yoshimasu、Nobuyuki Tanaka、Shigeaki Shioiri、Shigetoshi Shiota、Takayuki Yoneyama、Hitoshi Hamanaka：“用于正颌手术期间颌间固定的超弹性镍钛合金线的开发”日本口腔颌面外科杂志。

冨塚 謙一: "形状記憶合金を応用した顎骨組識内副子の機械的性質に関する研究" 口腔病学会雑誌. 58. 59-73 (1991)

Kenichi Tomizuka：“使用形状记忆合金研究内颌骨夹板的机械性能”口腔医学会杂志 58. 59-73 (1991)。

Kenich TOMITAUKA: "Study of mechanical properties of shape memory alloy plate for internal fixation of jaws" J. Stomato1. Soc., Jan.58. 59-73 (1991)

Kenich TOMITAUKA：“颌骨内固定用形状记忆合金板力学性能研究”J. Stomato1。