A Study of Hemodynamics on Exercise Stress Test in Children of High Risk Group for Hypertension and High Risk Group for Arteriosolerosis
A Study of Hemodynamics on Exercise Stress Test in Children of High Risk Group for Hypertension and High Risk Group for Arteriosolerosis
批准号:
01570531
负责人:
HANEDA Noriyuki
金额:
$1.47万
依托单位国家:
日本
项目类别:
Grant-in-Aid for General Scientific Research (C)
财政年份:
1989
资助国家:
日本
项目状态:
已结题
起止时间:
1989 至 1991
中文摘要
有很多文献证明,有一个追踪现象,即在同一年龄的儿童中,从小血压高的儿童,随着年龄的增长而血压高,同样地,血压低的儿童,最终血压也会降低。血清总胆固醇也是如此。因此,高血压或儿童食品中的高血清胆固醇水平,将来转变为高血压或高胆固醇血症的可能性很高。我们在研究的早期指出,超声心动图测量显示,被认为是这些疾病高危儿童的静息左心室舒张功能下降。去年对6 ~ 15岁儿童进行了运动负荷试验,并以同龄正常儿童作对照,用超声心动图分析了运动负荷时左室舒张功能。 ...更多信息 s研究。本研究采用运动负荷试验对9 ~ 18岁儿童左室舒张功能进行了研究。对3例高血压儿童、3例高胆固醇儿童和5例正常儿童进行运动负荷试验。超声心动图检测心功能。结果,与其他组相比,在高血压组中较早注意到心率和血压的增加。左心室对运动负荷的收缩增加足够,保留容量保持良好。有些病例通过运动负荷试验明确了左心室舒张功能的下降。将今年和去年的病例放在一起整体来看,即使在静息状态下,左室舒张功能也下降,包括校正的左室等容舒张时间延长和左室内径增加的峰值速度降低,运动负荷试验更是突出。高血清胆固醇组的运动负荷试验的重复性比高血压组的运动负荷试验的重复性高。我们的研究结果表明,在被认为属于高血压或动脉硬化高危组的儿童中,关注心功能潜在下降的临床过程观察的重要性。少
英文摘要
It is well documented that there is the tracking phenomenon, that is, children showing high blood pressure among the children of the same age from childhood have high blood pressure with the advance of age and likewise those showing low blood pressure have low blood pressure eventually. The same goes for serum totalcholesterol Where, therefore, high blood pressure or high serum cholesterol levels in childfood, the probability is high that they shift to hypertension or hypercholesterolemia in the future.It was pointed out in the early year of our study that a decline in the left ventricular diastolic function at rest was shown by echocardiographic measurement about children considered at high risk of these adiilt diseases. Last year oercise stress test with an ergoineter was done for 6 to 15-year old children belonging to that group and done for normal children of the same age as the control, and the left ventricular diastolic function on exercise loading analyzed by echocardiography wa … More s studied. This year Lhe study oil the left veiitricular diastolic function by exercise stress test with 9 to 18-year old children was continued as in last year. Exercise loading with an ergometer was done for 3 I)oys with high blood pressure, 3 boys with high serum cholesterol levels and 5 normal boys as the control. And the cardiac function was analyzed by echocardiography. As a result, an increase in the heart rate and blood pressure was noted early in the high blood pressure group as compared with other groups. An increase in the contraction of the left ventricle against exercise loading was sufficient and the reserved capacity was kept well. There were cases in which a decline in the left ventricular diastolic function was made clear by exercise stress test. When viewed on the whole with the cases of this year and cases of last year put together, a decline in the left ventricular diastolic function including prolongation of the corrected left ventricular isovolumic relaxation time and a decrease of the peak velosity of increase in the left ventricular dimnsion was noted even at rest and became prominent with exercise stress test. The reproducibility tend to be higher with exercise stress test on the high serum cholesterol level group than on the high blood pressure group.The results of our study suggest the importance of observations on the clinical course with attention paid to the latent decline in the cardiac function in children considered belonging to a high risk group for hypertension or arteriosclerosis. Less
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Chuzo Mori, Noriyuki Haneda, Kenji Kishida, Yurika Harada, Shiro Seto, Koji Watanabe & Toshikazu Nishino.: "Tracking of blood pressure and cholesterol in children - The Shimane Heart Study -" Presented at Interdisciplinary Symposium on Gene,. Nutrition an
森忠三、羽田典之、岸田贤治、原田由里香、濑户四郎、渡边浩二
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Koji Watanabe: "Relation between blood pressure,left ventricular mass and pulsed doppler purameters in healthy school children" Acta Paeditrica Japonica. 32. 275-281 (1990)
Koji Watanabe:“健康学童血压、左心室质量和脉冲多普勒血流计之间的关系”Acta Paedtrica Japonica。
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Yurika Hayashi: "Changes of left ventricular isovolumic relaxation time with growth in children." Acta Paediatrica Japonica. 32. 282-290 (1990)
Yurika Hayashi:“左心室等容舒张时间随儿童生长的变化。”
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Yurika Harada, Chuzu Mori, Koji Watanabe, Kenji Kishida, Noriyuki Haneda, Hajime Iwatani, & Toshikazu Nishio: "Left ventricular diastolic function of children in high blood pressure tracking group" Acta Padiatr Jpn. 32. 530-539 (1990)
原田由里香、森中祖、渡边浩二、岸田贤治、羽田典之、岩谷肇、
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Yurika Harada: "Left ventricular diastolic function of children in high blood pressure tracking group." Acta Paediatrica Japonica. 32. 530-539 (1990)
Yurika Harada:“高血压追踪组儿童的左心室舒张功能。”
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共 15 条
Us-Japan collaborative cohort study on cardiovascular risk factor in childhood
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批准号:05670677
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项目类别:Grant-in-Aid for General Scientific Research (C)
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资助金额:$1.02万
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财政年份:1993
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负责人:HANEDA Noriyuki
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依托单位:
海外基金