Diffusive personal samplers for hydrophilic solvents

用于亲水溶剂的扩散个人采样器

• 批准号: 02557030
• 负责人: IKEDA Masayuki
• 金额: $ 3.2万
• 依托单位: KYOTO UNIVERSITY
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Developmental Scientific Research (B)
• 财政年份: 1990
• 资助国家: 日本
• 起止时间: 1990 至 1992
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-02557030/
• 关键词: Acetone; Diffusive sampler; Hydrophilic solvent; Methanol; Methyl acetate; Personal sampler; 個人サンプラー; 拡散型サンプラー; ジメチルホルムアミド; 拡散型サンプラ-; 捕集剤; 捕集効率; 自然脱着; 個人曝露濃度; FTD-ガスクロマトグラフ; 個人サンプラ-; 親水性溶剤; メタノ-ル

Two of diffusive personal samplers have been successfully developed. One type takes advantage of 2 plastic disposable injection syringes (2.5 ml). One syringe is cut at 2 cm from the brim. Two brims are put together with porous membrane (Cellpore<@D1(] SY.encircledR.[)@>D1 NW-11) between them. Redistilled water, 2ml, is taken into the syringe, and water is exposed to ambient air through the membrane by keeping the needle joint part upward. In the case of the other sampler, silica gel A (20 to 30 mesh, 1.2 g) is taken into a phi 9 mm X 50 mm in length plastic cylinder. One end of the syrinder is closed, and the other end has a phi 5.7 mm window covered by the porous membrane. Solvent vapor exposure chambers of dynamic flow type was employed for experimental exposure. Exposure of water-equipped samplers to acetone vapors at up to 1000 ppm for up to 8 hours, or methanol vapors at up to 4000 ppm for up to 8 hours showed that the amount of solvent absorbed was proportional to the multiplication of the exposure concentration and exposure duration (i.e., CxT). Recovery after 15 min exposure at the maximum concentrations showed that the recovery was better than 80%. Similar exposure of silica gel-equipped samplers to methyl acetate vapors at up to 1600 ppm for up to 8 hours also showed that the amount adsorbed was proportional to CxT. Short-term peak exposure at 1600 ppm for 15 min showed a recovery of 108%. The experiments as a whole indicate that the water-equipped samplers can be applied for the monitoring of acetone and methanol vapors, and the silica gel-equipped one for methyl acetate monitoring in occupational health.

成功研制了两种扩散式个人采样器。一种是2支一次性塑料注射注射器（2.5毫升）。一个注射器在距杯沿2厘米处切开。两个帽檐用多孔膜(Cellpore<@D1（] SY.encircledR.）连接在一起。[)@>D1 NW-11]注射器中注入2ml蒸馏水，保持针头连接部分向上，水通过膜暴露于环境空气中。在其他取样器的情况下，硅胶A（20至30目，1.2 g）被放入长度为φ 9 mm X 50 mm的塑料圆筒中。筒体一端封闭，另一端有一个φ 5.7 mm的窗口，被多孔膜覆盖。实验暴露采用动态流型溶剂蒸汽暴露室。将装有水的采样器暴露在高达1000 ppm的丙酮蒸气中长达8小时，或暴露在高达4000 ppm的甲醇蒸气中长达8小时，表明溶剂的吸收量与暴露浓度和暴露持续时间（即CxT）的乘积成正比。在最大浓度下暴露15 min后的回收率大于80%。同样，将装有硅胶的样品暴露在高达1600 ppm的醋酸甲酯蒸气中长达8小时，也表明吸附量与CxT成正比。在1600 ppm下暴露15分钟的短期峰值显示出108%的回收率。实验结果表明，水装采样器可用于丙酮和甲醇蒸气的监测，硅胶装采样器可用于醋酸甲酯的监测。

项目成果

Y.UCHIDA,T.KAWAI,T.YASUGI and M.IKEDA: "Personal Monitoring Sampler for Acetone Vapor Exposure" Bull.Environ.Contam.Toxicol.44. 900-904 (1990)

Y.UCHIDA、T.KAWAI、T.YASUGI 和 M.IKEDA：“丙酮蒸气暴露个人监测采样器”Bull.Environ.Contam.Toxicol.44。

Y.Yasugi, T.Kawai, K.Mizunuma and M.Ikeda: "Diffusive personal samplers for Methyl Acetate Monitoring" Bull.Environ.Contam.Vol.49. 325-333 (1992)

Y.Yasugi、T.Kawai、K.Mizunuma 和 M.Ikeda：“用于乙酸甲酯监测的扩散个人采样器”Bull.Environ.Contam.Vol.49。

Kawai,T.et al.: "A personal diffusive sampler for occupational acetone vapor exposure monitoring" Toxicol.Lett.

Kawai,T.et al.：“用于职业丙酮蒸气暴露监测的个人扩散采样器”Toxicol.Lett。

T.YASUGI,T.KAWAI,K.MIZUNUMA and M.IKEDA: "Diffusive personal samplers for Methyl Acetate Monitoring" Bull.Environ.Contam.Toxicol.49. 325-333 (1992)

T.YASUGI、T.KAWAI、K.MIZUNUMA 和 M.IKEDA：“用于乙酸甲酯监测的扩散个人采样器”Bull.Environ.Contam.Toxicol.49。

T.Kawa, T.Yasugi, K.Mizunuma, S.Horiguchi Y.Hirase, Y.Uchida and M.ikeda: "Methanol in urine as a biological indicator of occupational exposure to methanol vapor" Int.Arch.Occup.Envir Health. Vol.63. 311-318 (1991)

T.Kawa、T.Yasugi、K.Mizunuma、S.Horiguchi Y.Hirase、Y.Uchida 和 M.ikeda：“尿液中的甲醇作为职业接触甲醇蒸气的生物指标” Int.Arch.Occup.Envir Health