Study of automated perimetry
Study of automated perimetry
批准号:
02670784
负责人:
MIYAKE Yozo
金额:
$1.34万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for General Scientific Research (C)
财政年份:
1990
资助国家:
日本
项目状态:
已结题
起止时间:
1990 至 1991
中文摘要
我们改进了一种自动投影静态视野计,它可以在光适应和暗适应状态下用三种不同波长的光测量阈值。该仪器可以在72度视场范围内分别评价杆式机构和锥式机构的相对状态。这些改进还使暗适应双色静态视野定量地跨越视野,包括轮廓测量。我们使用改进的Humphrey视野分析仪(HFA)测量一次脱离的视网膜的视锥和视杆阈值,研究静态敏感度的恢复。术前有黄斑受累或无黄斑受累的两组患者均进行了黄斑中心凹密度测定,术后黄斑敏感度恢复良好。术前HFA检测到的恶化以视杆敏感度丧失更为突出。视锥、视杆敏感度在术后1个月迅速恢复,6个月后逐渐恢复。直到术后3个月,杆状回旋慢于锥形回旋。在黄斑受累且术后黄斑敏感度恢复良好的患者中,视力的恢复情况各不相同。中心凹视锥密度计显示视力恢复差伴有视锥细胞色素再生不良。这些结果表明,黄斑脱离存在视锥外段功能异常,即使在心理物理敏感度恢复到正常水平时,这种异常也会持续存在于再附着的黄斑。
英文摘要
We modified an automated projection static perimeter which can measure thresholds with lights of three different wavelengths in light-adapted as well as in dark adapted state. This instrument can evaluate relative states of rod and cone mechanisms respectively within the visual field range of 72 degrees. These modifications also enable dark-adapted two-color static perimetry quantitatively across the visual field including profile measurement.We studied the recovery of static sensitivity using modified Humphrey Field Analyzer (HFA) to measure cone and rod threshold in once detached retina. Also foveal cone densitometry was done in two groups with or without preoperative macular involvement accompanied with a good postoperative recovery of macular sensitivity. Preoperative deterioration detected with HFA was more prominent in rod sensitivity loss. Cone and rod sensitivity recovered rapidly in postoperative one month, followed by gradual recovery up to six months. Rod rocovery was slower than cone until postoperative three months. Among patients with macular involvement and a good recovery of macular sensitivity after surgery, the recovery of visual acuity was variable. Foveal cone densitometry revealed that poor recovery of Visual acuity was accompanied by poor regeneration of cone pigments. These results suggest that functional abnormalities of cone outer segments are present in macular detachment which persist in reattached macula even when the psychophysical sensitivity recovers to normal level.
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矢ケ崎 克哉: "暗順応・明順応視野測定の臨床応用 1)装置の試作" 日本眼科学会雑誌. 94. 1162-1168 (1990)
Katsuya Yagasaki:“暗视和明视视野检查的临床应用1)装置的原型制作”日本眼科学会杂志94。1162-1168(1990)。
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矢ケ崎 克哉,三宅 養三: "裂孔原性網膜剥離の復位眼の視機能回復ー明順応・暗順応perimetryによる解析ー" 眼科臨床医報. 85. 2380-2390 (1991)
Katsuya Yagasaki、Yozo Miyake:“孔源性视网膜脱离复位眼的视觉功能恢复 - 使用明视和暗视视野检查进行分析”眼科临床通报 85. 2380-2390 (1991)。
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Yozo Miyake: "Lagir-by layer analysis of macular diseases with ofjectively measared visual functions" Jpn J Ophthalmal. 34. 225-238 (1990)
Yozo Miyake:“通过客观测量的视觉功能对黄斑疾病进行 Lagir 分层分析”Jpn J Olookingmal。
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Keisetsu Oh, Akira Saito, Yozo Miyake et al: "Development of a new measuring system for human cone pigment regeneration." Jpn J Med Electro Biol Engi.
Keisetsu Oh、Akira Saito、Yozo Miyake 等人:“开发一种新的人体视锥细胞色素再生测量系统。”
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Molecular genetic and pathophysiological study of new hereditary retinal diseases.
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批准号:13307048
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$30.2万
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财政年份:2001
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负责人:MIYAKE Yozo
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依托单位:
Layer-by-layer evaluation of function and morphology in macular diseases.
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批准号:11470363
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项目类别:Grant-in-Aid for Scientific Research (B).
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资助金额:$10.56万
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财政年份:1999
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负责人:MIYAKE Yozo
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依托单位:
Basic and clinical study of multifocal ERG
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批准号:08457462
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$4.67万
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财政年份:1996
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负责人:MIYAKE Yozo
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依托单位:
Study of the mechanism of visual function in incomplete type of congenital stationary night blindness
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批准号:06454496
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$2.94万
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财政年份:1994
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负责人:MIYAKE Yozo
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依托单位:
Study of diabetic maculopathy by focal lmacular ERG
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批准号:04454440
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$3.71万
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财政年份:1992
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负责人:MIYAKE Yozo
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依托单位:
Objective visual functions in macular diseases
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批准号:62480362
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项目类别:Grant-in-Aid for General Scientific Research (B)
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资助金额:$4.29万
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财政年份:1987
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负责人:MIYAKE Yozo
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依托单位: