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Study of automated perimetry

自动视野检查的研究

基本信息

批准号：
02670784
负责人：
MIYAKE Yozo
金额：
$ 1.34万
依托单位：
Nagoya University
依托单位国家：
日本
项目类别：
Grant-in-Aid for General Scientific Research (C)
财政年份：
1990
资助国家：
日本
起止时间：
1990 至 1991
项目状态：
已结题

项目摘要

We modified an automated projection static perimeter which can measure thresholds with lights of three different wavelengths in light-adapted as well as in dark adapted state. This instrument can evaluate relative states of rod and cone mechanisms respectively within the visual field range of 72 degrees. These modifications also enable dark-adapted two-color static perimetry quantitatively across the visual field including profile measurement.We studied the recovery of static sensitivity using modified Humphrey Field Analyzer (HFA) to measure cone and rod threshold in once detached retina. Also foveal cone densitometry was done in two groups with or without preoperative macular involvement accompanied with a good postoperative recovery of macular sensitivity. Preoperative deterioration detected with HFA was more prominent in rod sensitivity loss. Cone and rod sensitivity recovered rapidly in postoperative one month, followed by gradual recovery up to six months. Rod rocovery was slower than cone until postoperative three months. Among patients with macular involvement and a good recovery of macular sensitivity after surgery, the recovery of visual acuity was variable. Foveal cone densitometry revealed that poor recovery of Visual acuity was accompanied by poor regeneration of cone pigments. These results suggest that functional abnormalities of cone outer segments are present in macular detachment which persist in reattached macula even when the psychophysical sensitivity recovers to normal level.

我们改进了一种自动投影静态视野计，它可以在光适应和暗适应状态下用三种不同波长的光测量阈值。该仪器可在72 °视场范围内分别评价杆、锥机构的相对状态。这些修改也使暗适应的双色静态视野定量跨越整个视野，包括profilmeasurement.We研究了静态灵敏度的恢复，使用改进的Humphrey场分析仪（HFA）测量锥和杆阈值在一次脱离的视网膜。同时对术前有无黄斑病变的两组患者行中心凹圆锥密度测定，术后黄斑敏感度恢复良好。HFA检测到的术前恶化在杆敏感性丧失中更为突出。锥杆敏感性在术后1个月迅速恢复，随后逐渐恢复至6个月。直到术后3个月，棒的制作比锥慢。在黄斑受累和术后黄斑敏感性恢复良好的患者中，视力恢复情况各不相同。中心凹锥光密度测定显示，视力恢复不良伴随着锥色素再生不良。这些结果提示黄斑脱离时存在视锥细胞外节功能异常，即使心理生理敏感度恢复到正常水平，这种功能异常仍持续存在于复位后的黄斑中。