Refurbishment of a 400 MHz NMR spectrometer

400 MHz NMR 波谱仪的翻新

• 批准号: 524348822
• 金额: --
• 依托单位: Universität Münster
• 依托单位国家: 德国
• 项目类别: Major Research Instrumentation
• 财政年份: 2023
• 资助国家: 德国
• 起止时间: 2022-12-31 至 无数据
• 项目状态: 未结题
• 来源: https://gepris.dfg.de/gepris/projekt/524348822?language=en
• 关键词: Refurbishment; 400; MHz; NMR; spectrometer

NMR spectroscopy plays a key role in the characterization of chemical compounds, resulting in an enormous need for sophisticated methods at the Institute of Inorganic and Analytical Chemistry in the Department of Chemistry and Pharmacy at the Westfälische Wilhelms-Universität Münster due its diverse focal points. Current research at the institute in the field of main group element chemistry includes silicon ring compounds and silicon clusters with extraordinary properties. In the field of transition metal chemistry, the research groups deal, amongst others, with N-heterocyclic carbenes, with luminophores and the metal complexes obtained thereof, and with supramolecular aggregates and their applications as functional materials. In the field of bioinorganic chemistry, one focus is the development and characterization of artificial nucleic acids with metal-mediated base pairs. Furthermore, new synthetic methods for the preparation of nucleic acids with a boron-modified backbone are being developed. In collaboration with research groups from the MEET Battery Research Center, the mostly fluorine- and phosphorus-containing electrolytes of battery storage systems and their rearrangement, aging and decomposition products are characterized in detail. Furthermore, the NMR division at the Institute of Inorganic and Analytical Chemistry, which is part of the department-wide NMR center, is one of the general contacts for investigating inorganic and organometallic compounds as well as organic compounds containing phosphorus and fluorine. Without exception, these research areas have a high demand for different NMR methods. High-resolution spectra are required, for example, to determine the structure of complex silicon clusters, to characterize carefully small amounts of substances or compounds of low solubility, to investigate dynamic processes in solution, or for structure determinations. NMR spectroscopy allows a precise structure elucidation even when no crystalline material is available. The requested console will enable the institute to continue to carry out the large number of required measurements at a high level (e.g. NMR measurements accompanying syntheses, complete structure determinations using 1D and homo- or heteronuclear 2D NMR spectroscopy, time-consuming investigations of dynamic behavior). After the modernization, the 400 MHz NMR spectrometer will fulfill excellently the above-mentioned tasks and will reliably enable the application of urgently needed modern NMR methods with a wide measuring range and the measurement of numerous heteronuclei. The procurement is indispensable for the international competitiveness of research at the Department of Chemistry and Pharmacy in Münster and for the competent implementation of current and future projects with third-party funding.

核磁共振光谱学在化合物的表征中发挥着关键作用，因此，由于其关注的焦点不同，威斯特威廉大学化学和药剂系的无机化学和分析化学研究所对复杂方法的需求巨大。该研究所目前在主族元素化学领域的研究包括具有非凡性质的硅环化合物和硅簇。在过渡金属化学领域，除其他外，研究小组处理N-杂环卡宾、得到的发光体及其金属络合物、超分子聚集体及其作为功能材料的应用。在生物无机化学领域，一个焦点是金属介导的碱基对人工核酸的开发和表征。此外，正在开发制备具有硼修饰骨架的核酸的新的合成方法。与Meet电池研究中心的研究小组合作，对电池存储系统的主要含氟和含磷的电解液及其重排、老化和分解产物进行了详细的表征。此外，无机和分析化学研究所的核磁共振部是整个系核磁共振中心的一部分，是研究无机和有机金属化合物以及含磷和氟的有机化合物的一般联系人之一。无一例外，这些研究领域对不同的核磁共振方法有很高的要求。例如，需要高分辨率光谱来确定复杂的硅团簇的结构，仔细地表征少量低溶解度的物质或化合物，研究溶液中的动态过程，或者用于结构确定。即使在没有晶体材料的情况下，核磁共振波谱也可以进行精确的结构解析。所要求的控制台将使研究所能够继续在高水平上进行大量所需的测量(例如，伴随合成的核磁共振测量，使用一维和同核或异核二维核磁共振光谱分析的完整结构确定，耗时的动态行为研究)。改造后的400 MHz核磁共振波谱仪将很好地完成上述任务，并将可靠地应用于迫切需要的现代核磁共振方法，测量范围宽，并能测量大量的异核。采购对于明斯特化学和药剂系研究的国际竞争力以及在第三方资助下有效实施当前和未来的项目来说是不可或缺的。