Analysis of marginal and apical periodontal diseases and their systemic effects

苏达等用化学方法研究了实验性根尖周病变中防御反应的特点，并观察了中性粒细胞减少对病变发展的影响。Tanaka发现过氧化脂质参与根尖周病变的发展。Kawanami使用SEM观察到根尖孔周围的牙根外表面存在几种细菌。Kumagai在组织学上研究了实验诱导的狗牙髓牙周病变。Yamaki认为Ca（OH）_2作为根管内药物是有效的。Okamoto测量了牙周病细菌LPS刺激后单核细胞释放的几种细胞因子。石川证实了粘附分子在牙周病变中的表达。J.中村揭示，根管充填后根尖周组织愈合的刺激，通过解除咬合。Osada研究了从P ...更多信息 根尖肉芽肿Nishikawa发现测量牙周组织对牙齿撞击的脉冲响应可用于牙周组织疾病的诊断。H.中村研究了根管内细菌LPS对培养的牙髓细胞、牙周膜细胞和颅骨细胞的影响。Kimura发现，一些成人牙周炎患者在自体混合淋巴细胞反应中表现出较低的反应。Yoshikawa用化学方法研究了大鼠根尖肉芽肿中巨噬细胞的分布。Murayama发现，牙周袋中的黑色厌氧杆菌的种群密度因部位而异，即使在单个牙周袋中，牙龈卟啉单胞菌也存在DNA多态性。Matsuo分析了根尖周病变中免疫活性细胞数量与受累牙齿临床表现之间的相关性。Maeda利用原位杂交证实了在实验诱导的根尖周病变中存在IL-1 β mRNA表达细胞。横田洋三研究了交感神经对牙周组织的影响。少

Suda investigated immunohistochemically the characteristics of defense reactions in experimentally-induced rat periapical lesion and examined the effects of neutropenia on the development of the lesion. Tanaka found the involvement of lipid peroxides in the development of periapical lesion. Kawanami observed using SEM that several bacteria were present at the outer root surface around the apical foramen. Kumagai investigated histologically the experimentally-induced endodontal-periodontal lesions in dogs. Yamaki showed that Ca(OH)_2 used as an intracanal medicament was effective for clinical use. Okamoto measured the release of several cytokines from monocytes after the challenge of LPS from periodontopathic bacteria. Ishikawa demonstrated the expression of adhesion molecules in periodontal lesions. J. Nakamura revealed that periapical tissue healing following root canal filling was stimulated by disocclusion. Osada investigated some biological properties of fibroblasts cultured from p … More eriapical granulomas. Nishikawa found that the measurement of impulse-response of periodontium to tooth percussion was applicable for the diagnosis of the diseased conditions of periodontium. H. Nakamura investigated the effects of LPS from intracanal bacteria on cultured pulpal cells, periodontal ligament cells and calvarial cells. Kimura revealed that some adult periodontitis patients showed lower responses in autologous mixed lymphocyte reaction. Yoshikawa investigated immunohistochemically the distribution of macrophages in rat periapical granulomas. Murayama found that the population density of black-pigmented anaerobic rods in periodontal pocket varied from site to site and that there was DNA polymorphism of P. gingivalis even in a single pocket. Matsuo analyzed the correlations between the number of immunocompetent cells in periapical lesions and the clinical findings of the involved teeth. Maeda demonstrated the presence of IL-1beta mRNA-expressing cells in experimentally-induced periapical lesion using in situ hybridization. Yokota investigated the effects of sympathetic nerves on the periodontal tissue. Less