Mechanical Properties of Human Lumbar Intervertebral Discs and Design of an Artificial Structure to Substitute for the Mechanical Function
人体腰椎间盘的力学特性及替代力学功能的人工结构设计
基本信息
- 批准号:03650068
- 负责人:
- 金额:$ 1.34万
- 依托单位:
- 依托单位国家:日本
- 项目类别:Grant-in-Aid for General Scientific Research (C)
- 财政年份:1991
- 资助国家:日本
- 起止时间:1991 至 1992
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
The human spine is composed of many vertebrae and intervertebral discs, and has the complex structure and three dimensional geometry. Because the motion of trunk is due to the elastic deformation of intervertebral discs which have also shockabsorbing ability between vertebrae, intervertebral discs are subjected to a considerable variety of forces and moments. In particular, the lumbar spine is subjected to a larger load and more complex movement than the other sections. The lumbar disc, therefore, is the most important component to maintain stability and mobility of the lumbar spine. Many diseases of human lumbar spine are often caused by the mechanical factors of disc, as disc degeneration and disc injuries. Therefore, useful information in biomechanical researches must be produced on the lumbar spine. The purpose of this study is to investigate the mechanical properties of the human lumbar intervertebral discs and to design an artificial structure to substitute for the mechanical function. First, the static loading response of L4/5 disc was confirmed by the cyclic axial compression-tension test and the cyclic axial torsion test within the range of physiological loads. Next, a method of the estimation of elastic modulus at a local region in a disc was presented. In addition, the state of strain occurring on the sagittal plane of a disc in vivo was evaluated under flexion and extension. Finally, a new artificial intervertebral disc was proposed to reconstruct the stability and mobility of the mechanical function of a human lumbar disc.
人体脊柱由许多椎骨和椎间盘组成,具有复杂的结构和三维几何形状。由于躯干的运动是由于椎间盘的弹性变形引起的,而椎间盘在椎体之间又具有减震能力,因此椎间盘承受着各种各样的力和力矩。特别是,腰椎比其他部位承受更大的负荷和更复杂的运动。因此,腰椎间盘是维持腰椎稳定和活动的最重要的组成部分。人类腰椎的许多疾病往往是由椎间盘的力学因素引起的,如椎间盘退变、椎间盘损伤等。因此,在腰椎的生物力学研究中必须提供有用的信息。本研究的目的是研究人类腰椎间盘的力学特性,并设计一种人工结构来替代其力学功能。首先,在生理载荷范围内,通过循环轴向压拉试验和循环轴向扭转试验验证L4/5盘的静载荷响应。其次,提出了一种圆盘局部区域弹性模量的估计方法。此外,在屈曲和伸展的情况下,评估了在体内椎间盘矢状面发生的应变状态。最后,提出了一种新的人工椎间盘来重建人类腰椎间盘机械功能的稳定性和可动性。
项目成果
期刊论文数量(22)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
S.Tadano: "Structure and Materials for a Synthetic Intervertebral Disc" Proceedings of 7th International Conference on Biomedical Engineering. 243-245 (1992)
S.Tadano:“合成椎间盘的结构和材料”第七届国际生物医学工程会议论文集。
- DOI:
- 发表时间:
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- 影响因子:0
- 作者:
- 通讯作者:
S.Tadano: "On the structure and the Geometry of an Artificial Intervertebral Disc" 1991 Advances in Bioengineering. 20. 129-132 (1991)
S.Tadano:“论人工椎间盘的结构和几何形状”1991 年生物工程进展。
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- 影响因子:0
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但野 茂: "脊椎の計算バイオメカニクス" 日本ME学会誌「BME」. 6. 42-51 (1992)
多田野茂:“脊柱的计算生物力学”日本 ME 学会杂志“BME”6. 42-51 (1992)。
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
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- 通讯作者:
S.TADANO: "Structure Materials for a synthetic Intervertebral Disc" Proceedings of 7th International Conference on Biomedical Engineering. 243-245 (1992)
S.TADANO:“合成椎间盘的结构材料”第七届国际生物医学工程会议论文集。
- DOI:
- 发表时间:
- 期刊:
- 影响因子:0
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- 通讯作者:
但野 茂: "脊椎不安定性の生体力学的評価法" 日本機械学会論文集. 58. 1073-1079 (1992)
多田野茂:《脊柱不稳定的生物力学评价方法》日本机械工程学会会刊 58. 1073-1079 (1992)。
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Strength and Stress Characterization based on Mechanical Interaction between Mineral and Collagen Components in Bone tissue
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19200035 - 财政年份:2007
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12555036 - 财政年份:2000
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$ 1.34万 - 项目类别:
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Research on X-ray measurements of Remodeling Stress in Living Bone Tissue
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- 批准号:
12480254 - 财政年份:2000
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$ 1.34万 - 项目类别:
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Research on Individual Design Simulator to Develop Home Care Equipment fitted Personal Physical Properties
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09555050 - 财政年份:1997
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$ 1.34万 - 项目类别:
Grant-in-Aid for Scientific Research (B)
Research on Constitutive Laws of Lumbar Intervertebral Disc with Biphasic Thoery
双相理论研究腰椎间盘的本构规律
- 批准号:
08458279 - 财政年份:1996
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$ 1.34万 - 项目类别:
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相似海外基金
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