A study of three endemic diseases in rural areas of Northeast Thailand

我们调查了泰国东北部Khon Kaen地区村庄的腹泻、寄生虫病、尿石症以及食物和饮用水。腹泻组；一项问卷调查显示，93%的居民使用储存在容器中的雨水饮用，其中22%或28%的人回答在饮用前过滤和/或煮沸水。一项微生物调查表明，从储存雨水的容器中收集的饮用水样品中有一半以上被某些肠致病性细菌污染。本研究最富有成效的结果是从环境和人类粪便样本中分离出一种新的霍乱弧菌O139，即孟加拉霍乱弧菌。寄生虫病组：4个村寄生虫平均感染率28.5%。2个村在治疗9个月后进行了重新调查，其中以蛇胸虫（21.4%）感染率最高，其次为钩虫和棘孔虫。东都村的弓形虫感染率较治疗前有所下降，而Khokklang村的弓形虫感染率没有变化。孔敬区沼泽鳗鱼未检出尖牙颌口蝇幼虫。尿石症组：367人接受腹部超声检查（US）。39人（10.6%）出现异常；肾结石31例（8.4%），肾积水16例（4.4%），肾囊肿1例（0.3%）。我们比较了结石患者和健康对照组的尿液生化成分。然而，结石患者和健康对照组的尿液成分没有显著差异。食品和饮用水组：对当地传统食品中的细菌进行了调查。芽孢杆菌是鱼露和kapi-paste等调味品中最占优势的属。在泰国常用的食品制剂kapi-paste、nam-pla和pla-kem中检出10株产肠毒素蜡样芽孢杆菌。少

We surveyed diarrhea, parasitic diseases, urolithiasis, and food and drinking water in villages in Khon Kaen district in northeast Thailand.Diarrhea team ; A questionnaire study indicated that 93% of the residents used rain water stored in a container for drinking and that 22 or 28% of them answered that they filtrate and/or boil water before drinking it. A microbiological survey indicated that more than half of drinking water samples collected from containers storing rain were contaminated with some kinds of enteropathogenic bacteria. The most fruitful results of this study was that some strains of a new species of Vibrio sp., V.cholerae O139, synonyms Bengal cholerae, were isolated from both environmental and human fecal samples.Parasitic disease team : Average infection rate of parasites at 4 villages was 28.5%. Prevalence of Opisthorchis viverrini (21.4%) was highest, followed in order by hookworm and Echinostoma sp. Re-survey 9 months after treatment was carried out in 2 villages. … More The prevalence of O.viverrini in Dondoo Village decreased from that before treatment, whereas that in Khokklang Village didn't change. No larvae of Gnathostoma spinigerm were detected in swamp eels collected in Khon Kaen District.Urolithiasis team : Three hundred and sixty-seven persons were examined by abdominal ultrasound (US). Abnormal findings were detected in 39 persons (10.6%) ; renal calculi in 31 persons (8.4%), hydronephrosis in 16 persons (4.4%), and renal cyst in one person (0.3%). We compared urinary biochemical composition of stone formers with healthy controls. However, there was no significant difference between the urinary compositions of stone formers and healthy controls.Food and drinking water team : Bacteria in local traditional foods were investigated. Bacillus was the most dominant genus in condiments such as nam-pla (fish sauce) and kapi-paste. Ten strains of enterotoxin-producing Bacillus cereus were detected in kapi-paste, nam-pla and pla-kem, which are commonly used for food preparation in Thailand. Less