TACTILE SENSOR FOR BREAST TUMOR DIAGNOSTIC SYSTEM.

用于乳腺肿瘤诊断系统的触觉传感器。

• 批准号: 04557053
• 负责人: ABE Rikiya
• 金额: $ 8.64万
• 依托单位: FUKUSHIMA MEDICAL COLLEGE
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Developmental Scientific Research (B)
• 财政年份: 1992
• 资助国家: 日本
• 起止时间: 1992 至 1994
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-04557053/
• 关键词: tactile sensor; resonance frequency; DELTAf; stiffness; displacement sensor; breast cancer; collagen matrix; clinical diagnostic system; 多センサー型プローブ; 三次元画像化; 知覚用触覚センサ; 乳腺腫瘍; 圧電素子

Background) Palpation has been an important diagnostic maneuver for breast lesions, but no objective evaluation has been measured. New tactile sensor or pyezoelectric transducer (PZT) can measure consistency without destroying an object, cause touching lightly. We tried to use the newly deviced tactile sensor, and evaluate consistency in order to confirm the breast lesions.Basic ExaminationMaterials and Methods) Two kinds of consistency parameter were employed for basic examination. One was change in frequency (DELTAf). PZT vibrating in its own resonance frequency is changed after it has brought into contact with objects, and the other was stiffness (St) showing degree of deformity of object by compression.Soft tissue makes resonance frequency of PZT decrease, and St needs low degree of compression, corresponding its consistence. In the case of hard matrix such as the nail or the teeth, make it increase, and St needs high degree of compression. We measured consistency of the breast can … More cer and its surrounding tissue on the cutting surface of the fresh resected specimen for basic study about character of their consistency. Materials were the specimen from thirtyfour cases of breast cancer. The two parameters were measured on the tissue of carcinoma, normal mammary galnd and adipose surrounding the carcinoma on the cutting surface of the fresh resected sample. The measurement was done at two or three points in each portion.Results) The average DELTAf in invasive ductal carcinoma, invasive ductal carcinoma with a predominant intraductal component, normal mammary gland, adipose tissue were -445 Hz, -695 Hz, -888 Hz, -966 Hz, respectively. Difference of the consistency in each part of specimen was also measured in St, 19.5g/cm, 13.5g/cm, 3.6g/cm, 2.0g/cm, respectively.Conclusion) These results suggested that the new tactile sensor had ability to not only differentiate an existence of tumor in the breast, also determinate the characteristics of each tumor according to amount of involved collagen matrix in it.2.Clinical ExaminationOn the basis of these results, we made a clinical diagnostic system for breast cancer. This system is constistuted in probe, encorder, bed and personal computor. The probe has two devices, which are tactile sensor and displacement sensor. They are connected with pressure sensor and coordinate sensor. Four pairs of tactile and displacement sensor were arranged linearly on the top of the probe. Scanning was done from nipple to peripheral direction and cover the whole breast. Nine patients with palpable breast tumor were measured by this new system. Five cases of tumors could be detected by this system, but this system was not able to distinct cancer from benign tumor. Now we're making another diagnostic system using this tactile sensor. Less

背景）触诊是诊断乳腺病变的一个重要手段，但还没有客观的评估方法。新的触觉传感器或压电传感器（PZT）可以在不破坏物体的情况下测量一致性，轻轻触摸。我们尝试使用新研制的触觉传感器，并评估一致性，以确定乳腺病变。一个是频率变化（Δ f）。PZT在与物体接触后，以自身的共振频率振动，另一个是反映物体受压缩变形程度的刚度（St），软组织使PZT的共振频率降低，St需要低的压缩度，与其一致性相对应。在硬基质如指甲或牙齿的情况下，使其增加，并且St需要高度压缩。我们测量了乳房的硬度 ...更多信息 新鲜标本切割面上牙槽骨及其周围组织的稠度特性进行基础研究。材料为34例乳腺癌标本。在新鲜乳腺切除标本的切面上，分别对癌组织、正常乳腺组织和癌周脂肪组织进行了测量。结果）浸润性导管癌、以导管内成分为主的浸润性导管癌、正常乳腺、脂肪组织的平均DELTAf分别为-445Hz、-695Hz、-888Hz、-966Hz。结果表明，该触觉传感器不仅能区分乳腺肿瘤的存在，而且能区分乳腺肿瘤的大小，并根据肿瘤中胶原基质的含量确定肿瘤的特征。2.临床检查在这些结果的基础上，我们做了一个乳腺癌的临床诊断系统。该系统由探头、编码器、床和微机组成。该探头有两个器件，分别是触觉传感器和位移传感器。它们与压力传感器和坐标传感器相连。四对触觉和位移传感器线性排列在探针的顶部。扫描从乳头向周围方向进行，覆盖整个乳房。应用该系统对9例乳腺肿块患者进行了测量。该系统可以检测到5例肿瘤，但该系统不能区分癌症和良性肿瘤。现在我们正在用这个触觉传感器制造另一个诊断系统。少

项目成果

原潔: "硬さセンサーの乳癌診断への応用" 乳癌の臨床. 11. 78-79 (1996)

Kiyoshi Hara：“硬度传感器在乳腺癌诊断中的应用”Breast Cancer Clinical 11. 78-79 (1996)。

阿部力哉: "硬さセンサーの乳癌診断への応用" 学術月報. 48. 106-106 (1995)

阿部力也：《硬度传感器在乳腺癌诊断中的应用》学术月报48。106-106（1995）。

尾股 定夫: "圧電素子を利用した硬さ測定用触覚センサー" 超音波TECHNO. 4. 37-41 (1992)

Sadao Omata：“使用压电元件进行硬度测量的触觉传感器”超声波技术 4. 37-41 (1992)。