TACTILE SENSOR FOR BREAST TUMOR DIAGNOSTIC SYSTEM.

背景)触诊已成为乳腺病变的重要诊断手段，但目前尚无客观评价方法。新型触觉传感器或光电传感器(PZT)可以在不破坏物体的情况下测量一致性，导致轻微触摸。我们尝试使用新研制的触觉传感器，并评估一致性，以确定乳房病变。基本检查材料和方法)使用两种一致性参数进行基本检查。一个是频率变化(DELTAf)。PZT与物体接触后，自身振动的共振频率发生变化，另一个是反映物体受压缩变形程度的刚度(ST)，软组织使PZT的共振频率降低，ST需要较低的压缩程度，与之对应。对于坚硬的基质，如指甲或牙齿，要使其增大，ST需要高度压缩。我们测量了乳房罐头…的一致性新鲜切除标本切面上有较多的CER及其周围组织，用于基础研究其粘附性。材料为34例乳腺癌标本。对新鲜切除标本切面上的癌组织、正常乳腺组织和癌周脂肪组织进行了两个参数的测量。结果)浸润性导管癌、以导管内成分为主的浸润性导管癌、正常乳腺、脂肪组织的平均DELTAf分别为-445、-695、-888、-966 Hz。结果表明，这种新型触觉传感器不仅可以区分乳腺肿瘤的存在，还可以根据乳腺组织中胶原基质的含量判断肿瘤的性质。2.临床检验在此基础上，建立了乳腺癌的临床诊断系统。该系统由探头、记录仪、床和个人计算机组成。探头有两个装置，分别是触觉传感器和位移传感器。它们分别与压力传感器和坐标传感器相连。四对触觉和位移传感器线性布置在探头的顶部。扫描从乳头到周缘，覆盖整个乳房。用该系统对9例可触及的乳腺肿瘤患者进行了测量。该系统能检出5例肿瘤，但不能区分良性肿瘤和癌。现在，我们正在制造另一个使用这种触觉传感器的诊断系统。较少

Background) Palpation has been an important diagnostic maneuver for breast lesions, but no objective evaluation has been measured. New tactile sensor or pyezoelectric transducer (PZT) can measure consistency without destroying an object, cause touching lightly. We tried to use the newly deviced tactile sensor, and evaluate consistency in order to confirm the breast lesions.Basic ExaminationMaterials and Methods) Two kinds of consistency parameter were employed for basic examination. One was change in frequency (DELTAf). PZT vibrating in its own resonance frequency is changed after it has brought into contact with objects, and the other was stiffness (St) showing degree of deformity of object by compression.Soft tissue makes resonance frequency of PZT decrease, and St needs low degree of compression, corresponding its consistence. In the case of hard matrix such as the nail or the teeth, make it increase, and St needs high degree of compression. We measured consistency of the breast can … More cer and its surrounding tissue on the cutting surface of the fresh resected specimen for basic study about character of their consistency. Materials were the specimen from thirtyfour cases of breast cancer. The two parameters were measured on the tissue of carcinoma, normal mammary galnd and adipose surrounding the carcinoma on the cutting surface of the fresh resected sample. The measurement was done at two or three points in each portion.Results) The average DELTAf in invasive ductal carcinoma, invasive ductal carcinoma with a predominant intraductal component, normal mammary gland, adipose tissue were -445 Hz, -695 Hz, -888 Hz, -966 Hz, respectively. Difference of the consistency in each part of specimen was also measured in St, 19.5g/cm, 13.5g/cm, 3.6g/cm, 2.0g/cm, respectively.Conclusion) These results suggested that the new tactile sensor had ability to not only differentiate an existence of tumor in the breast, also determinate the characteristics of each tumor according to amount of involved collagen matrix in it.2.Clinical ExaminationOn the basis of these results, we made a clinical diagnostic system for breast cancer. This system is constistuted in probe, encorder, bed and personal computor. The probe has two devices, which are tactile sensor and displacement sensor. They are connected with pressure sensor and coordinate sensor. Four pairs of tactile and displacement sensor were arranged linearly on the top of the probe. Scanning was done from nipple to peripheral direction and cover the whole breast. Nine patients with palpable breast tumor were measured by this new system. Five cases of tumors could be detected by this system, but this system was not able to distinct cancer from benign tumor. Now we're making another diagnostic system using this tactile sensor. Less